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Summary Expression Phenotypes Gene Literature (203) GO Terms (15) Nucleotides (389) Proteins (76) Interactants (193) Wiki
XB-GENEPAGE-494199

grin1     glutamate ionotropic receptor NMDA type subunit 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: grin1 assayed (9 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (50 sources): Abnormal pyramidal sign, Absent speech, Agenesis of corpus callosum, Cerebellar atrophy, Cerebral atrophy, Cerebral cortical atrophy, Cerebral visual impairment, Chorea, Constipation, Decreased body weight, [+]
Mouse (98 sources): abnormal AMPA-mediated synaptic currents, abnormal NMDA-mediated synaptic currents, abnormal anxiety-related response, abnormal behavioral response to addictive substance, abnormal behavioral response to alcohol, abnormal behavioral response to xenobiotic, abnormal brain wave pattern, abnormal breathing pattern, abnormal conditioned taste aversion behavior, abnormal contextual conditioning behavior, [+]

View all ortholog results at Monarch