shc1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-494861

Gene Symbol: shc1 Gene Name: SHC (Src homology 2 domain containing) transforming protein 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (41 sources): abnormal actin cytoskeleton morphology, abnormal atrioventricular cushion morphology, abnormal carotid artery morphology, abnormal cell adhesion, abnormal cell morphology, abnormal double-negative T cell morphology, abnormal excitatory postsynaptic potential, abnormal locomotor coordination, abnormal muscle spindle morphology, abnormal vascular endothelial cell morphology, abnormal vascular smooth muscle morphology, abnormal vitelline vasculature morphology, decreased angiogenesis, decreased brain size, decreased cardiac muscle contractility, decreased cellular sensitivity to hydrogen peroxide, decreased cellular sensitivity to oxidative stress, decreased cellular sensitivity to ultraviolet irradiation, decreased double-positive T cell number, decreased muscle spindle number, decreased single-positive T cell number, decreased susceptibility to atherosclerosis, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, enlarged pericardium, extended life span, growth/size/body region phenotype, heart vascular congestion, homeostasis/metabolism phenotype, impaired limb coordination, increased vasodilation, no abnormal phenotype detected, oxidative stress, pale yolk sac, prenatal lethality, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, thin myocardium, thin ventricular wall, trabecula carnea hypoplasia, vascular smooth muscle hypoplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (41 sources): abnormal actin cytoskeleton morphology, abnormal atrioventricular cushion morphology, abnormal carotid artery morphology, abnormal cell adhesion, abnormal cell morphology, abnormal double-negative T cell morphology, abnormal excitatory postsynaptic potential, abnormal locomotor coordination, abnormal muscle spindle morphology, abnormal vascular endothelial cell morphology, [+]