was Phenotypes

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Phenotypes

Gene Literature (74)

Nucleotides (99)

Interactants (344)

XB-GENEPAGE-5759990

Gene Symbol: was Gene Name: WASP actin nucleation promoting factor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: was assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (81 sources): Abnormal delayed hypersensitivity skin test, Abnormal eosinophil morphology, Abnormal platelet function, Abnormal platelet morphology, Abnormality of the menstrual cycle, Abnormality of the musculature, Abnormality of the skin, Absent microvilli on the surface of peripheral blood lymphocytes, Acute leukemia, Anemia, Arrhythmia, Arthritis, Autoimmunity, Blepharitis, Bruising susceptibility, Chest pain, Chronic diarrhea, Chronic leukemia, Chronic otitis media, Chronic pulmonary obstruction, Congenital thrombocytopenia, Conjunctivitis, Decreased circulating total IgM, Decreased mean platelet volume, Decreased specific anti-polysaccharide antibody level, Diarrhea, Dyspnea, Eczematoid dermatitis, Epistaxis, Fatigue, Fever, Gingival bleeding, Glomerulopathy, Hematemesis, Hematochezia, Hemolytic anemia, Hyperostosis, Hypoplasia of the thymus, Immunodeficiency, Increased circulating IgA level, Increased circulating IgE level, Inflammation of the large intestine, Intermittent thrombocytopenia, Internal hemorrhage, Intracranial hemorrhage, Iron deficiency anemia, Joint hemorrhage, Keratitis, Large vessel vasculitis, Lymphoma, Lymphopenia, Melena, Meningitis, Microcytic anemia, Monocytopenia, Neoplasm, Nephropathy, Neutropenia, Oral bleeding, Otitis media, Peripheral neuropathy, Petechiae, Pneumonia, Prolonged bleeding time, Purpura, Recurrent bacterial infections, Recurrent intrapulmonary hemorrhage, Recurrent lower respiratory tract infections, Recurrent respiratory infections, Recurrent upper respiratory tract infections, Reduced lymphocyte surface expression of CD43, Sepsis, Sinusitis, Skin ulcer, Small vessel vasculitis, Specific learning disability, Spontaneous hematomas, Sudden cardiac death, Thrombocytopenia, Urticaria, Vasculitis [+]
Mouse (36 sources): abnormal B cell proliferation, abnormal bone marrow cell morphology/development, abnormal cell migration, abnormal crypts of Lieberkuhn morphology, abnormal dendritic cell antigen presentation, abnormal dendritic cell morphology, abnormal dendritic cell physiology, abnormal double-negative T cell morphology, abnormal double-positive T cell morphology, abnormal glomerular mesangium morphology, abnormal kidney morphology, abnormal megakaryocyte morphology, abnormal osteoclast differentiation, abnormal osteoclast physiology, abnormal renal corpuscle morphology, abnormal thymocyte activation, crypts of Lieberkuhn abscesses, decreased T cell proliferation, decreased double-positive T cell number, decreased follicular B cell number, decreased marginal zone B cell number, decreased mature B cell number, immune system phenotype, increased anti-chromatin antibody level, increased anti-double stranded DNA antibody level, increased anti-single stranded DNA antibody level, increased autoantibody level, increased follicular B cell number, increased germinal center B cell number, increased mesangial cell number, increased neutrophil cell number, increased plasma cell number, increased splenocyte number, lymphoid hypoplasia, renal glomerular immunoglobulin deposits, spleen hyperplasia [+]
View all ortholog results at Monarch