lig3 Phenotypes

Phenotypes

XB-GENEPAGE-5788003

Gene Symbol: lig3 Gene Name: ligase III, DNA, ATP-dependent

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: lig3 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (22 sources): abnormal astrocyte morphology, abnormal astrocyte physiology, abnormal cellular respiration, abnormal cerebellum development, abnormal myocardial fiber morphology, abnormal neuron differentiation, abnormal neuronal precursor proliferation, decreased brain size, decreased cardiac muscle contractility, decreased cerebellar granule cell number, decreased embryo size, decreased oligodendrocyte number, dilated heart atrium, dilated heart ventricle, elevated level of mitotic sister chromatid exchange, embryonic growth retardation, embryonic lethality between implantation and somite formation, incomplete penetrance, embryonic lethality between somite formation and embryo turning, incomplete penetrance, postnatal lethality, complete penetrance, premature death, small cerebellum, thin ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (22 sources): abnormal astrocyte morphology, abnormal astrocyte physiology, abnormal cellular respiration, abnormal cerebellum development, abnormal myocardial fiber morphology, abnormal neuron differentiation, abnormal neuronal precursor proliferation, decreased brain size, decreased cardiac muscle contractility, decreased cerebellar granule cell number, [+]