| Monarch Ortholog Phenotypes
|
Human (26 sources):
Abdominal pain,
Arthralgia,
Arthritis,
Conjunctivitis,
Dehydration,
Disseminated intravascular coagulation,
Dysesthesia,
Enterocolitis,
Erythema,
Failure to thrive,
Fatigue,
Fever,
Headache,
Hyperhidrosis,
Increased circulating ferritin concentration,
Myalgia,
Nausea and vomiting,
Pancytopenia,
Polydipsia,
Pruritus,
Secretory diarrhea,
Sensorineural hearing impairment,
Short stature,
Skin rash,
Splenomegaly,
Urticaria
[+]
|
|
Mouse (11 sources):
abnormal cell death,
abnormal macrophage physiology,
abnormal response to infection,
decreased interleukin-1 beta secretion,
dermatitis,
immune system phenotype,
increased circulating interleukin-1 beta level,
increased circulating interleukin-17 level,
increased interleukin-1 beta secretion,
increased neutrophil cell number,
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.