Monarch Ortholog Phenotypes
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Mouse (45 sources):
abnormal angiogenesis,
abnormal apoptosis,
abnormal brain development,
abnormal digestive system development,
abnormal dorsal aorta morphology,
abnormal endocardium morphology,
abnormal head mesenchyme morphology,
abnormal heart development,
abnormal intersomitic vessel morphology,
abnormal myocardium compact layer morphology,
abnormal placenta labyrinth morphology,
abnormal placenta vasculature,
abnormal placental labyrinth vasculature morphology,
abnormal septum transversum morphology,
abnormal vascular development,
abnormal vascular endothelial cell development,
abnormal vascular endothelial cell morphology,
abnormal vascular permeability,
abnormal vascular smooth muscle morphology,
abnormal vitelline vascular remodeling,
abnormal vitelline vasculature morphology,
absent vitelline blood vessels,
atrioventricular septal defect,
decreased angiogenesis,
decreased embryo size,
decreased heart right ventricle size,
distended pericardium,
double outlet right ventricle with atrioventricular septal defect,
embryonic growth arrest,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
failure of heart looping,
failure of vascular branching,
head tilt,
increased fibroblast apoptosis,
myocardial fiber degeneration,
no abnormal phenotype detected,
pale yolk sac,
pericardial edema,
premature death,
small first pharyngeal arch,
small heart,
small second pharyngeal arch,
thin myocardium,
trabecula carnea hypoplasia
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