Monarch Ortholog Phenotypes
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Mouse (36 sources):
abnormal B cell activation,
abnormal B cell proliferation,
abnormal CD4-positive, alpha-beta T cell physiology,
abnormal humoral immune response,
abnormal mature B cell morphology,
abnormal peripheral B cell anergy,
abnormal transitional stage B cell morphology,
absent mature B cells,
arrested B cell differentiation,
autoimmune response,
decreased B cell proliferation,
decreased B-2 B cell number,
decreased IgG1 level,
decreased IgG3 level,
decreased cell migration,
decreased marginal zone B cell number,
decreased mature B cell number,
decreased memory B cell number,
decreased transitional stage B cell number,
decreased transitional stage T1 B cell number,
decreased transitional stage T2 B cell number,
hydrometra,
immune system phenotype,
increased B cell apoptosis,
increased B cell proliferation,
increased B-1 B cell number,
increased B-1a cell number,
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased CD8-positive, alpha-beta memory T cell number,
increased IgG1 level,
increased IgG2a level,
increased activation-induced B cell apoptosis,
increased anti-double stranded DNA antibody level,
increased neutrophil cell number,
premature death,
small superior vagus ganglion
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