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Summary Expression Phenotypes Gene Literature (5) GO Terms (13) Nucleotides (144) Proteins (28) Interactants (429) Wiki

kdm2a     lysine (K)-specific demethylase 2A

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal axis elongation (1 source), abnormal gastrulation (1 source), abnormal head morphology (1 source), abnormal tail morphology (1 source), abnormally delayed closure of blastopore (1 source), decreased length of anterior-posterior axis (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: kdm2a assayed (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + kdm2a MO (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (12 sources): abnormal embryonic neuroepithelium morphology, abnormal heart looping, abnormal neuron proliferation, decreased embryo size, delayed neural tube closure, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, impaired neuron differentiation, incomplete embryo turning, increased neural crest cell apoptosis, [+]