| Monarch Ortholog Phenotypes
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Human (43 sources):
Abnormal cardiac septum morphology,
Abnormal pinna morphology,
Anal atresia,
Anal stenosis,
Aortic regurgitation,
Bicornuate uterus,
Bicuspid aortic valve,
Broad forehead,
Broad nasal tip,
Bulbous nose,
Clinodactyly of the 5th finger,
Clitoral hypertrophy,
Craniosynostosis,
Duane anomaly,
Ectopic kidney,
Eyelid coloboma,
Horseshoe kidney,
Hypoplasia of the radius,
Intrauterine growth retardation,
Labial hypoplasia,
Lop ear,
Low-set ears,
Macular dystrophy,
Mitral atresia,
Myopia,
Narrow nose,
Pelvic kidney,
Peripheral pulmonary artery stenosis,
Pulmonary artery stenosis,
Rectovaginal fistula,
Renal agenesis,
Renal insufficiency,
Retinal dystrophy,
Seizure,
Short stature,
Small for gestational age,
Spina bifida occulta,
Syringomyelia,
Telecanthus,
Thin upper lip vermilion,
Toe syndactyly,
Vesicoureteral reflux,
Wide nasal bridge
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Mouse (4 sources):
abnormal embryo size,
embryonic lethality prior to organogenesis,
embryonic lethality prior to tooth bud stage,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.