Monarch Ortholog Phenotypes
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Mouse (38 sources):
abnormal axon morphology,
abnormal external male genitalia morphology,
abnormal gastrocnemius morphology,
abnormal lumbar dorsal root ganglion morphology,
abnormal mitochondrial ATP synthesis coupled electron transport,
abnormal mitochondrial physiology,
abnormal motor capabilities/coordination/movement,
abnormal muscle electrophysiology,
abnormal muscle fiber morphology,
abnormal physical strength,
abnormal redox activity,
abnormal skeletal muscle fiber type ratio,
abnormal skeletal muscle morphology,
abnormal soleus morphology,
chromatolysis,
decreased gastrocnemius weight,
decreased grip strength,
decreased locomotor activity,
decreased mean corpuscular hemoglobin,
decreased motor neuron number,
decreased skeletal muscle fiber number,
decreased soleus weight,
decreased tibialis anterior weight,
impaired limb coordination,
increased spinal cord apoptosis,
increased thermal nociceptive threshold,
increased variability of skeletal muscle fiber size,
limb grasping,
microgliosis,
nervous system phenotype,
positive geotaxis,
premature death,
skeletal muscle fiber atrophy,
skeletal muscle fiber degeneration,
skeletal muscle fibrosis,
small dorsal root ganglion,
small L4 dorsal root ganglion,
small L5 dorsal root ganglion
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