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Summary Expression Phenotypes Gene Literature (132) GO Terms (18) Nucleotides (92) Proteins (39) Interactants (721) Wiki

thra     thyroid hormone receptor alpha

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally peramorphic growth of hindlimb bud (4 sources), increased size of the hindlimb bud (4 sources), abnormal hindlimb bud (2 sources), increased thickness of the epidermis (2 sources), increased width of hindlimb bud (2 sources), abnormal iridophore (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: thra assayed (2 sources)
Computed annotations: thra assayed (4 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + thra TALEN (5 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (19 sources): Anemia, Broad-based gait, Congenital hip dislocation, Congenital hypothyroidism, Constipation, Delayed eruption of teeth, Delayed skeletal maturation, Drowsiness, Dry skin, Growth delay, [+]
Mouse (118 sources): abnormal Purkinje cell dendrite morphology, abnormal adipose tissue amount, abnormal bone mineral content, abnormal bone mineralization, abnormal bone remodeling, abnormal bone strength, abnormal cerebellum external granule cell layer morphology, abnormal chondrocyte physiology, abnormal cochlear outer hair cell morphology, abnormal contextual conditioning behavior, [+]

View all ortholog results at Monarch