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XB-GENEPAGE-5966550
thra thyroid hormone receptor alpha
Anatomical Phenotypes
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abnormally peramorphic growth of hindlimb bud (4 sources), increased size of the hindlimb bud (4 sources), abnormal hindlimb bud (2 sources), delayed metamorphosis (2 sources), increased thickness of the epidermis (2 sources), increased width of hindlimb bud (2 sources), abnormal iridophore (1 source), abnormal regulation of growth rate (1 source), abnormal thyroid hormone metabolic process (1 source), decreased apoptosis in tail (1 source), decreased apoptosis in tail somite (1 source), decreased length of hindlimb (1 source), decreased width of the head (1 source), increased apoptosis in tail somite (1 source) |
Expression Phenotypes
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Manual annotations: thra manipulated (1 source), thra assayed (2 sources) |
Experiments (Reagents)
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Xla Wt + thra TALEN (5 sources), Xtr wt + thra TALEN + mCherry (3 sources), Xla wt + Tg(thradn) + GFP (2 sources), Xla Wt + Tg(thradn) (1 source), Xtr Wt + TALEN thra (1 source) |
Monarch Ortholog Phenotypes
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Human (19 sources): Anemia, Broad-based gait, Congenital hip dislocation, Congenital hypothyroidism, Constipation, Delayed eruption of teeth, Delayed skeletal maturation, Drowsiness, Dry skin, Growth delay, [+] |
Mouse (118 sources): abnormal adipose tissue amount, abnormal bone mineral content, abnormal bone mineralization, abnormal bone remodeling, abnormal bone strength, abnormal cerebellum external granule cell layer morphology, abnormal chondrocyte physiology, abnormal cochlear outer hair cell morphology, abnormal contextual conditioning behavior, abnormal defecation, [+] |
View all ortholog results at Monarch |