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Summary Expression Phenotypes Gene Literature (94) GO Terms (4) Nucleotides (140) Proteins (21) Interactants (192) Wiki
XB-GENEPAGE-5994597

chrna4     cholinergic receptor, nicotinic alpha 4

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: chrna4 assayed (9 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (3 sources): Focal-onset seizure, Intellectual disability, Seizure
Mouse (27 sources): abnormal behavioral response to addictive substance, abnormal brain wave pattern, abnormal inhibitory postsynaptic currents, abnormal locomotor activation, abnormal motor learning, abnormal nicotine-mediated receptor currents, abnormal response to new environment, abnormal synaptic dopamine release, behavior/neurological phenotype, behavioral arrest, [+]

View all ortholog results at Monarch