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Summary Expression Phenotypes Gene Literature (3) GO Terms (6) Nucleotides (71) Proteins (37) Interactants (197) Wiki

plekhg5     pleckstrin homology and RhoGEF domain containing G5

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: plekhg5 assayed (35 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (23 sources): Abnormal lower motor neuron morphology, Abnormality of the foot, Areflexia, Decreased motor nerve conduction velocity, Decreased number of large peripheral myelinated nerve fibers, Difficulty climbing stairs, Difficulty walking, Distal amyotrophy, Distal muscle weakness, Distal sensory impairment, [+]
Mouse (9 sources): abnormal angiogenesis, abnormal artery development, abnormal coronary vessel morphology, abnormal kidney blood vessel morphology, abnormal vascular endothelial cell morphology, decreased angiogenesis, decreased ventricle muscle contractility, impaired skin barrier function, increased vascular permeability

View all ortholog results at Monarch