tert Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (78)

Nucleotides (101)

Interactants (311)

XB-GENEPAGE-6451332

Gene Symbol: tert Gene Name: telomerase reverse transcriptase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tert assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (79 sources): Abnormal blistering of the skin, Abnormal eyebrow morphology, Abnormal eyelash morphology, Abnormal fingernail morphology, Abnormal leukocyte morphology, Abnormal morphology of female internal genitalia, Abnormal testis morphology, Abnormality of coagulation, Abnormality of neutrophils, Abnormality of the dentition, Abnormality of the pharynx, Anemia, Anorectal anomaly, Aplasia/Hypoplasia of the skin, Aplastic/hypoplastic toenail, Ataxia, Avascular necrosis, Blepharitis, Bone marrow hypocellularity, Carious teeth, Cataract, Cellular immunodeficiency, Cerebellar hypoplasia, Cerebral calcification, Cerebral cortical atrophy, Cirrhosis, Coarse metaphyseal trabecularization, Dermal atrophy, Diabetes mellitus, Displacement of the urethral meatus, Esophageal stricture, Excessive wrinkled skin, Failure to thrive, Generalized hyperpigmentation, Generalized hypopigmentation of hair, Global developmental delay, Hearing impairment, Hepatic failure, Hepatomegaly, Hyperhidrosis, Hypermelanotic macule, Hypodontia, Hypopigmented skin patches, Hypoplasia of the maxilla, Hyporeflexia, Immunodeficiency, Intellectual disability, Intrauterine growth retardation, Lymphoma, Macule, Malabsorption, Menorrhagia, Microcephaly, Nail dystrophy, Neoplasm, Neoplasm of the pancreas, Oral leukoplakia, Osteoporosis, Palmoplantar keratoderma, Periodontitis, Premature graying of hair, Recurrent fractures, Recurrent respiratory infections, Scoliosis, Short stature, Skin ulcer, Skin vesicle, Sparse hair, Sparse scalp hair, Spasticity, Splenomegaly, Taurodontia, Telangiectasia of the skin, Thrombocytopenia, Tracheoesophageal fistula, Urethral stenosis, Ventriculomegaly, White hair, obsolete Hypotrichosis [+]
Mouse (33 sources): abnormal chromosome morphology, abnormal crypts of Lieberkuhn morphology, abnormal male germ cell apoptosis, abnormal neuron differentiation, abnormal neuronal precursor proliferation, abnormal telomere length, aneuploidy, cellular phenotype, chromosomal instability, decreased brain weight, decreased cell proliferation, decreased incidence of tumors by chemical induction, decreased litter size, decreased liver tumor incidence, decreased lung fibroblast proliferation, decreased oligodendrocyte number, decreased spleen weight, decreased telomere length, decreased testis weight, early cellular replicative senescence, enhanced wound healing, impaired olfaction, increased apoptosis, increased incidence of tumors by chemical induction, increased small intestinal crypt cell apoptosis, lumbar vertebral transformation, no abnormal phenotype detected, premature death, reduced fertility, skin hyperplasia, spleen atrophy, taste/olfaction phenotype, thoracic vertebral transformation [+]
View all ortholog results at Monarch