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XB-GENEPAGE-6459062
kmt5c lysine (K)-specific methyltransferase 5C
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal multiciliated cell morphology (7 sources), abnormal embryo morphology (5 sources), abnormally decreased number of cilium in the ciliated cell (4 sources), decreased length of tail (3 sources), abnormal histone methylation (2 sources), abnormal ciliary axoneme morphology (1 source), abnormal cilium motility (1 source), abnormal development of basal body (1 source), abnormal main body axis morphology (1 source), abnormal multiciliated cell (1 source), absent swimming behavior (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: kmt5c manipulated (3 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + kmt5c MO + kmt5b MO (H1/H2 double KD) (9 sources), Xtr Wt + kmt5b MO + kmt5c MO (H1/H2KD) (1 source), Xla Wt + kmt5c MO (suv4-20h2) (0 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (1 source): no abnormal phenotype detected |