tgif1 Phenotypes

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Phenotypes

Gene Literature (6)

Nucleotides (160)

Interactants (283)

XB-GENEPAGE-853020

Gene Symbol: tgif1 Gene Name: TGFB induced factor homeobox 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal bending of tail (1 source), abnormal development of embryo (1 source), abnormal tail morphology (1 source), edematous ventral trunk (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tgif1 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + tgif1 MO (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (42 sources): Abnormal cardiovascular system morphology, Absent nasal septal cartilage, Agenesis of corpus callosum, Ambiguous genitalia, Anteverted nares, Asthma, Choanal atresia, Cleft palate, Cyclopia, Depressed nasal bridge, Depressed nasal tip, Duodenal atresia, EMG: myopathic abnormalities, Hemangioma, Holoprosencephaly, Hypoplasia of penis, Hypotelorism, Hypothyroidism, Intellectual disability, Intrauterine growth retardation, Iris coloboma, Maternal diabetes, Median cleft lip and palate, Median cleft upper lip, Microcephaly, Midnasal stenosis, Narrow nasal bridge, Orofacial cleft, Panhypopituitarism, Premature birth, Ptosis, Renal agenesis, Scoliosis, Seizure, Semilobar holoprosencephaly, Short nose, Short philtrum, Short stature, Solitary median maxillary central incisor, Strabismus, Tented upper lip vermilion, Tetralogy of Fallot [+]
Mouse (33 sources): abnormal brain development, abnormal cytokine level, abnormal folding of telencephalic vesicles, abnormal forebrain development, abnormal hindbrain development, abnormal midface morphology, abnormal pinna reflex, abnormal placenta intervillous maternal lacunae morphology, abnormal placenta labyrinth morphology, abnormal pregnancy, abnormal response to vitamins, abnormal snout morphology, abnormal upper lip morphology, conductive hearing loss, deafness, decreased body size, decreased cell proliferation, embryonic growth retardation, embryonic lethality during organogenesis, incomplete penetrance, increased middle ear goblet cell number, increased or absent threshold for auditory brainstem response, increased placenta intervillous maternal lacunae size, increased susceptibility to otitis media, kinked tail, middle ear effusion, middle ear polyps, no abnormal phenotype detected, prenatal lethality, incomplete penetrance, preweaning lethality, incomplete penetrance, reduced female fertility, situs ambiguus, situs inversus, small brain ventricles [+]
View all ortholog results at Monarch