Monarch Ortholog Phenotypes
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Mouse (26 sources):
abnormal astrocyte morphology,
abnormal cell morphology,
abnormal cerebral cortex morphology,
abnormal cortical plate morphology,
abnormal depression-related behavior,
abnormal excitatory postsynaptic potential,
abnormal nervous system development,
abnormal neuronal precursor proliferation,
abnormal neuron differentiation,
abnormal NMDA-mediated synaptic currents,
abnormal telencephalon development,
behavior/neurological phenotype,
decreased cell proliferation,
decreased inner cell mass proliferation,
decreased neuronal precursor cell number,
decreased neuron number,
embryonic lethality between implantation and placentation, complete penetrance,
embryonic lethality between implantation and somite formation, complete penetrance,
increased CD4-positive, alpha beta T cell number,
increased neuron apoptosis,
increased neuron number,
increased startle reflex,
loss of cortex neurons,
no abnormal phenotype detected,
postnatal lethality, complete penetrance,
preweaning lethality, complete penetrance
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