setdb1 Phenotypes

Phenotypes

XB-GENEPAGE-853379

Gene Symbol: setdb1 Gene Name: SET domain bifurcated 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal NMDA-mediated synaptic currents, abnormal astrocyte morphology, abnormal cell morphology, abnormal cerebral cortex morphology, abnormal cortical plate morphology, abnormal depression-related behavior, abnormal excitatory postsynaptic potential, abnormal nervous system development, abnormal neuron differentiation, abnormal neuronal precursor proliferation, abnormal telencephalon development, behavior/neurological phenotype, decreased cell proliferation, decreased inner cell mass proliferation, decreased neuron number, decreased neuronal precursor cell number, embryonic lethality between implantation and placentation, complete penetrance, embryonic lethality between implantation and somite formation, complete penetrance, increased CD4-positive, alpha beta T cell number, increased neuron apoptosis, increased neuron number, increased startle reflex, loss of cortex neurons, no abnormal phenotype detected, postnatal lethality, complete penetrance, preweaning lethality, complete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (26 sources): abnormal NMDA-mediated synaptic currents, abnormal astrocyte morphology, abnormal cell morphology, abnormal cerebral cortex morphology, abnormal cortical plate morphology, abnormal depression-related behavior, abnormal excitatory postsynaptic potential, abnormal nervous system development, abnormal neuron differentiation, abnormal neuronal precursor proliferation, [+]