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Summary Expression Phenotypes Gene Literature (1) GO Terms (9) Nucleotides (106) Proteins (46) Interactants (29) Wiki
XB-GENEPAGE-876386

irak2     interleukin 1 receptor associated kinase 2

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: irak2 assayed (6 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (9 sources): abnormal chemokine level, abnormal macrophage physiology, decreased circulating interleukin-6 level, decreased circulating tumor necrosis factor level, decreased interferon-alpha secretion, decreased interleukin-6 secretion, decreased sensitivity to induced morbidity/mortality, decreased susceptibility to endotoxin shock, decreased tumor necrosis factor secretion