Monarch Ortholog Phenotypes
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Human (35 sources):
Abnormality of the digestive system,
Abnormality of the immune system,
Airway obstruction,
Asplenia,
Asthma,
Atelectasis,
Bronchiectasis,
Chronic bronchitis,
Chronic otitis media,
Chronic sinusitis,
Clubbing of fingers,
Conductive hearing impairment,
Corneal dystrophy,
Cough,
Delayed speech and language development,
Ectopic pregnancy,
Glue ear,
Halitosis,
Headache,
Hydrocephalus,
Immotile cilia,
Impaired nasal mucociliary clearance,
Infertility,
Miscarriage,
Nasal polyposis,
Pectus excavatum,
Pneumonia,
Recurrent respiratory infections,
Reduced sperm motility,
Respiratory distress,
Rhinitis,
Scoliosis,
Situs inversus totalis,
Tachypnea,
Ventriculomegaly
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Mouse (36 sources):
abnormal brain development,
abnormal brain ependyma morphology,
abnormal brain ventricle morphology,
abnormal choroid plexus morphology,
abnormal embryonic cilium location or orientation,
abnormal left-right axis patterning,
abnormal neuron differentiation,
abnormal olfactory bulb development,
abnormal postnatal subventricular zone morphology,
abnormal primitive node morphology,
abnormal rostral migratory stream morphology,
abnormal stomach position or orientation,
absent brain ependyma motile cilia,
absent nodal flow,
absent oviduct epithelium motile cilium,
absent respiratory motile cilia,
absent sperm flagellum,
aorta hypoplasia,
cardiovascular system phenotype,
decreased birth body size,
decreased CD4-positive, alpha beta T cell number,
decreased embryonic cilium length,
decreased fetal weight,
decreased locomotor activity,
fetal growth retardation,
immune system phenotype,
increased single-positive T cell number,
lethality throughout fetal growth and development, incomplete penetrance,
lymphoid hypoplasia,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
right pulmonary isomerism,
right-sided stomach,
situs inversus,
slow postnatal weight gain,
small olfactory bulb
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View all ortholog results at Monarch
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