cd3e Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (7)

Nucleotides (144)

Interactants (96)

XB-GENEPAGE-919748

Gene Symbol: cd3e Gene Name: CD3e molecule

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (28 sources): Anorexia, Chronic oral candidiasis, Decreased circulating IgG level, Decreased circulating total IgA, Decreased lymphocyte proliferation in response to mitogen, Decreased proportion of CD3-positive T cells, Defective T cell proliferation, Diarrhea, Eosinophilia, Erythroderma, Failure to thrive secondary to recurrent infections, Fever, Hepatitis, Hepatosplenomegaly, Immunodeficiency, Increased circulating antibody level, Lymphopenia, Otitis media, Pneumonia, Protracted diarrhea, Recurrent abscess formation, Recurrent candida infections, Recurrent gastroenteritis, Recurrent herpes, Recurrent infections, Recurrent otitis media, Recurrent pneumonia, Recurrent respiratory infections [+]
Mouse (20 sources): abnormal CD8-positive, alpha-beta T cell differentiation, abnormal T cell differentiation, abnormal class switch recombination, abnormal double-negative T cell morphology, abnormal double-positive T cell morphology, abnormal regulatory T cell physiology, abnormal thymus morphology, absent CD4-positive, alpha beta T cells, absent T cells, arrested T cell differentiation, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased double-positive T cell number, increased CD8-positive, alpha-beta T cell number, increased DN3 thymocyte number, increased T cell apoptosis, increased central memory CD8 positive, alpha-beta T cell number, increased double-negative T cell number, increased sensitivity to induced morbidity/mortality, small thymus [+]
View all ortholog results at Monarch