| Monarch Ortholog Phenotypes
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Human (1 source):
Moderate albuminuria
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Mouse (31 sources):
abnormal adipose tissue amount,
abnormal axon extension,
abnormal body length,
abnormal bone mineralization,
abnormal brain development,
abnormal circulating alkaline phosphatase level,
abnormal dentate gyrus subgranular zone morphology,
abnormal lean body mass,
abnormal locomotor activation,
abnormal retina blood vessel morphology,
abnormal retina vasculature morphology,
abnormal sleep behavior,
decreased body length,
decreased bone mineral content,
decreased brain size,
decreased brain weight,
decreased circulating glucose level,
decreased lean body mass,
decreased neuron number,
decreased thigmotaxis,
enlarged lateral ventricles,
growth/size/body region phenotype,
impaired neuron differentiation,
increased systemic arterial systolic blood pressure,
increased total body fat amount,
irregularly shaped pupil,
nervous system phenotype,
preweaning lethality, complete penetrance,
reduced fertility,
shortened ST segment,
small hippocampus
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.