clcn3 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-950793

Gene Symbol: clcn3 Gene Name: chloride channel, voltage-sensitive 3

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (41 sources): abnormal abdominal fat pad morphology, abnormal astrocyte morphology, abnormal behavioral response to xenobiotic, abnormal entorhinal cortex morphology, abnormal excitatory postsynaptic currents, abnormal excitatory postsynaptic potential, abnormal eye electrophysiology, abnormal heart echocardiography feature, abnormal hippocampus pyramidal cell morphology, abnormal microglial cell physiology, abnormal motor capabilities/coordination/movement, abnormal myocardial fiber physiology, abnormal response to new environment, abnormal retina neuronal layer morphology, abnormal synaptic vesicle morphology, decreased brain size, decreased cerebral cortex pyramidal cell number, decreased circulating glucose level, decreased hippocampus pyramidal cell number, decreased retina photoreceptor cell number, decreased susceptibility to pharmacologically induced seizures, decreased ventricle muscle contractility, disorganized photoreceptor outer segment, enhanced behavioral response to xenobiotic, enlarged lateral ventricles, hippocampal neuron degeneration, hippocampus atrophy, impaired neutrophil phagocytosis, impaired synaptic plasticity, increased heart weight, increased sensitivity to induced morbidity/mortality, lethality at weaning, incomplete penetrance, loss of GABAergic neurons, myocardium hypertrophy, photoreceptor inner segment degeneration, photoreceptor outer segment degeneration, premature death, reduced fertility, reduced male fertility, renal/urinary system phenotype, small hippocampus [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (41 sources): abnormal abdominal fat pad morphology, abnormal astrocyte morphology, abnormal behavioral response to xenobiotic, abnormal entorhinal cortex morphology, abnormal excitatory postsynaptic currents, abnormal excitatory postsynaptic potential, abnormal eye electrophysiology, abnormal heart echocardiography feature, abnormal hippocampus pyramidal cell morphology, abnormal microglial cell physiology, [+]