Chronic constipation, Cognitive impairment, Constipation, Cow milk allergy, Cryptorchidism, Depressed nasal bridge, Developmental regression, Dilation of Virchow-Robin spaces, Drooling, Dysphagia, Elevated circulating hepatic transaminase concentration, Epileptic encephalopathy, Failure to thrive, Feeding difficulties, Flat occiput, Frontal bossing, Gastroesophageal reflux, Generalized hypotonia, Gingival bleeding, Gluten intolerance, Hearing impairment, High anterior hairline, High-pitched cry, Hyperactivity, Hyperventilation, Hyporeflexia, Hypotonia, Hypsarrhythmia, Infantile muscular hypotonia, Infra-orbital crease, Intellectual disability, severe, Long philtrum, Mandibular prognathia, Motor stereotypy, Plagiocephaly, Pointed chin, Poor speech, Precocious puberty, Prominent glabella, Protruding tongue, Pulmonic stenosis, Scoliosis, Seizure, Self-injurious behavior, Severe global developmental delay, Sleep-wake cycle disturbance, Strabismus, Telecanthus, Thin upper lip vermilion, Tricuspid regurgitation, Ventricular septal defect, Wide mouth, obsolete Impaired social interactions

decreased grip strength, decreased prepulse inhibition, decreased pulmonary respiratory rate, decreased synaptic glutamate release, enlarged stomach, increased grooming behavior, increased lean body mass, no abnormal phenotype detected, small thymus