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Summary Expression Phenotypes Gene Literature (10) GO Terms (0) Nucleotides (97) Proteins (32) Interactants (136) Wiki
XB-GENEPAGE-954329

sp7     Sp7 transcription factor

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sp7 assayed (19 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (31 sources): Abnormality of cardiovascular system morphology, Biconcave flattened vertebrae, Blue sclerae, Bowing of limbs due to multiple fractures, Brachyturricephaly, Delayed eruption of teeth, Dentinogenesis imperfecta, Depressed nasal bridge, Facial asymmetry, Femoral bowing present at birth, straightening with time, [+]
Mouse (8 sources): abnormal bone mineralization, abnormal limb morphology, abnormal osteoblast differentiation, abnormal skeleton development, failure of bone ossification, failure of endochondral bone ossification, neonatal lethality, complete penetrance, no abnormal phenotype detected

View all ortholog results at Monarch