acadl Phenotypes

Phenotypes

XB-GENEPAGE-958718

Gene Symbol: acadl Gene Name: acyl-CoA dehydrogenase long chain

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (31 sources): Atrial flutter, Autistic behavior, Cardiac arrest, Decreased 3-hydroxyacyl-CoA dehydrogenase level, Decreased circulating carnitine concentration, Dicarboxylic aciduria, Elevated creatine kinase after exercise, EMG: myopathic abnormalities, Exercise-induced myoglobinuria, Exercise-induced rhabdomyolysis, Fatigable weakness, Feeding difficulties, Generalized hypotonia, Generalized muscle weakness, Hepatic steatosis, Hepatocellular necrosis, Hepatomegaly, Hyperammonemia, Hypertrophic cardiomyopathy, Hypothermia, Lethargy, Mild expressive language delay, Muscle stiffness, Myalgia, Myopathy, Nonketotic hypoglycemia, Prolonged neonatal jaundice, Prolonged QT interval, Sudden cardiac death, Tachypnea, Vomiting [+]
Mouse (13 sources): abnormal adaptive thermogenesis, abnormal bile composition, abnormal lipid homeostasis, cardiac fibrosis, decreased litter size, increased circulating carnitine level, increased fatty acids level, increased unsaturated fatty acids level, lipidosis, macrovesicular hepatic steatosis, microvesicular hepatic steatosis, premature death, prenatal lethality, incomplete penetrance [+]
View all ortholog results at Monarch