arhgef4 Phenotypes

Phenotypes

XB-GENEPAGE-960462

Gene Symbol: arhgef4 Gene Name: Rho guanine nucleotide exchange factor 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: arhgef4 assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (22 sources): abnormal response to tactile stimuli, abnormal tumor morphology, abnormal tumor vascularization, abnormal vascular endothelial cell migration, abnormal vascular endothelial cell physiology, abnormal vibrissa morphology, decreased angiogenesis, decreased circulating alanine transaminase level, decreased circulating alkaline phosphatase level, decreased circulating free fatty acids level, decreased circulating fructosamine level, decreased grip strength, decreased hemoglobin content, decreased IgG1 level, decreased mean corpuscular hemoglobin, decreased tumor growth/size, increased circulating alkaline phosphatase level, increased heart weight, increased lactate dehydrogenase level, increased lean body mass, increased mature B cell number, no abnormal phenotype detected [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (22 sources): abnormal response to tactile stimuli, abnormal tumor morphology, abnormal tumor vascularization, abnormal vascular endothelial cell migration, abnormal vascular endothelial cell physiology, abnormal vibrissa morphology, decreased angiogenesis, decreased circulating alanine transaminase level, decreased circulating alkaline phosphatase level, decreased circulating free fatty acids level, [+]