Monarch Ortholog Phenotypes
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Human (5 sources):
Acanthosis nigricans,
Accelerated skeletal maturation,
Insulin resistance,
Obesity,
Premature pubarche
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Mouse (26 sources):
abnormal abdominal fat pad morphology,
abnormal amniotic fluid composition,
abnormal circulating cholesterol level,
abnormal corticosterone level,
abnormal epididymal fat pad morphology,
abnormal fibroblast proliferation,
abnormal food intake,
abnormal lipid homeostasis,
abnormal lung development,
abnormal pulmonary alveolus morphology,
abnormal spatial learning,
absent alveolar lamellar bodies,
decreased alveolar lamellar body number,
decreased circulating glucose level,
decreased collagen level,
decreased surfactant secretion,
decreased susceptibility to weight gain,
growth/size/body region phenotype,
homeostasis/metabolism phenotype,
improved glucose tolerance,
increased fibroblast proliferation,
increased food intake,
increased subcutaneous adipose tissue amount,
liver/biliary system phenotype,
muscle phenotype,
small alveolar lamellar bodies
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View all ortholog results at Monarch
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