pde4b Phenotypes

Phenotypes

XB-GENEPAGE-963511

Gene Symbol: pde4b Gene Name: phosphodiesterase 4B

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pde4b assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (22 sources): abnormal CNS synaptic transmission, abnormal dendritic spine morphology, abnormal learning/memory/conditioning, abnormal neuron differentiation, abnormal object recognition memory, abnormal spatial working memory, behavior/neurological phenotype, brain vacuoles, cardiovascular system phenotype, decreased anxiety-related response, decreased sensitivity to induced morbidity/mortality, decreased synaptic depression, decreased tumor necrosis factor secretion, enhanced learning, enhanced long term potentiation, impaired cued conditioning behavior, impaired neutrophil recruitment, increased exploration in new environment, increased post-tetanic potentiation, increased vertical activity, nervous system phenotype, taste/olfaction phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (22 sources): abnormal CNS synaptic transmission, abnormal dendritic spine morphology, abnormal learning/memory/conditioning, abnormal neuron differentiation, abnormal object recognition memory, abnormal spatial working memory, behavior/neurological phenotype, brain vacuoles, cardiovascular system phenotype, decreased anxiety-related response, [+]