relb Phenotypes

Summary

Expression

Phenotypes

Gene Literature (6)

XB-GENEPAGE-964071

Gene Symbol: relb Gene Name: v-rel avian reticuloendotheliosis viral oncogene homolog B

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: relb assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (71 sources): abnormal Peyer's patch morphology, abnormal antigen presentation, abnormal bile duct morphology, abnormal cell-mediated immunity, abnormal cytokine level, abnormal cytotoxic T cell physiology, abnormal definitive hematopoiesis, abnormal epidermis stratum corneum morphology, abnormal erythropoiesis, abnormal gamma-delta T cell morphology, abnormal hepatobiliary system morphology, abnormal humoral immune response, abnormal immune system organ morphology, abnormal interferon level, abnormal interleukin level, abnormal keratinocyte apoptosis, abnormal keratinocyte physiology, abnormal macrophage physiology, abnormal mesenteric lymph node morphology, abnormal proerythroblast morphology, abnormal tumor necrosis factor level, absent Peyer's patches, absent lymph nodes, absent thymus medulla, acanthosis, decreased B cell proliferation, decreased NK T cell number, decreased Peyer's patch number, decreased T cell proliferation, decreased body size, decreased circulating amylase level, decreased circulating interleukin-4 level, decreased dendritic cell number, decreased interleukin-17 secretion, decreased pre-B cell number, decreased spleen white pulp amount, decreased susceptibility to type IV hypersensitivity reaction, dermatitis, disheveled coat, epidermal hyperplasia, epididymal inflammation, hunched posture, immune system phenotype, impaired neutrophil phagocytosis, increased bone marrow cell number, increased granulocyte number, increased keratinocyte proliferation, increased macrophage cell number, increased respiratory mucosa goblet cell number, increased spleen red pulp amount, increased spleen weight, increased susceptibility to Riboviria infection, lethality at weaning, complete penetrance, mixed cellular infiltration to dermis, myeloid hyperplasia, ovary inflammation, pale liver, pathological neovascularization, premature death, preweaning lethality, incomplete penetrance, pulmonary alveolar hemorrhage, reduced fertility, ruffled hair, salivary gland inflammation, skin edema, small Peyer's patches, spleen hyperplasia, thick dermal layer, thick skin, thin tail, thymus atrophy [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (71 sources): abnormal Peyer's patch morphology, abnormal antigen presentation, abnormal bile duct morphology, abnormal cell-mediated immunity, abnormal cytokine level, abnormal cytotoxic T cell physiology, abnormal definitive hematopoiesis, abnormal epidermis stratum corneum morphology, abnormal erythropoiesis, abnormal gamma-delta T cell morphology, [+]