pak2 Phenotypes

Phenotypes

XB-GENEPAGE-966301

Gene Symbol: pak2 Gene Name: p21 protein (Cdc42/Rac)-activated kinase 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased size of the eye (1 source), decreased size of the forebrain (1 source), decreased size of the midbrain (1 source)

Diseases Diseases from the human disease ontology (DO) manually associated with phenotypes from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
disease of mental health (2AP sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + pak2 MO (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (21 sources): abnormal actin cytoskeleton morphology, abnormal cell death, abnormal excitatory postsynaptic potential, abnormal hematopoietic stem cell physiology, abnormal postsynaptic density morphology, abnormal response to social novelty, abnormal social investigation, behavior/neurological phenotype, decreased dendritic spine density, decreased embryo size, embryonic growth retardation, embryonic lethality prior to tooth bud stage, impaired somite development, increased fibroblast proliferation, increased grooming behavior, increased mean corpuscular hemoglobin, open neural tube, preweaning lethality, complete penetrance, prolonged RR interval, reduced long term potentiation, social withdrawal [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (21 sources): abnormal actin cytoskeleton morphology, abnormal cell death, abnormal excitatory postsynaptic potential, abnormal hematopoietic stem cell physiology, abnormal postsynaptic density morphology, abnormal response to social novelty, abnormal social investigation, behavior/neurological phenotype, decreased dendritic spine density, decreased embryo size, [+]