| Monarch Ortholog Phenotypes
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Human (40 sources):
Abnormality of the musculature,
Arrhythmia,
Atrioventricular block,
Bradycardia,
Cardiomyopathy,
Cardiorespiratory arrest,
Coma,
Cyanosis,
Decreased plasma carnitine,
Decreased urine output,
Dicarboxylic aciduria,
Elevated creatine kinase after exercise,
Elevated hepatic transaminase,
Elevated plasma acylcarnitine levels,
Elevated serum creatine kinase,
Encephalopathy,
Fasting hypoglycemia,
Generalized hypotonia,
Global developmental delay,
Hepatic failure,
Hepatomegaly,
Hyperammonemia,
Hypoglycemia,
Hypoketotic hypoglycemia,
Hypotension,
Hypothermia,
Irritability,
Lethargy,
Microcephaly,
Muscle weakness,
Muscular hypotonia,
Nystagmus,
Preeclampsia,
Respiratory insufficiency,
Rhabdomyolysis,
Seizure,
Sudden episodic apnea,
Ventricular extrasystoles,
Ventricular hypertrophy,
Ventricular tachycardia
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Mouse (14 sources):
abnormal Mullerian duct morphology,
abnormal Wolffian duct topology,
abnormal dorsal pancreas topology,
abnormal vitelline vein topology,
double ureter,
ductus venosus stenosis,
embryo cyst,
herniated liver,
jugular vein stenosis,
multiple persisting craniopharyngeal ducts,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.