vldlr Phenotypes

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Phenotypes

Gene Literature (8)

Nucleotides (259)

Interactants (87)

XB-GENEPAGE-971957

Gene Symbol: vldlr Gene Name: very low density lipoprotein receptor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: vldlr assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (34 sources): Abnormality of metabolism/homeostasis, Abnormality of movement, Abnormality of the orbital region, Abnormality of vision, Ataxia, Broad-based gait, Cataract, Cerebellar atrophy, Cerebellar hypoplasia, Cerebral palsy, Delayed speech and language development, Dysarthria, Dysdiadochokinesis, Dysmetria, Gait ataxia, Gait disturbance, Gaze-evoked nystagmus, Generalized hypotonia, Global developmental delay, Hyperreflexia, Hypoplasia of the brainstem, Hypotonia, Intellectual disability, Intention tremor, Pachygyria, Pes planus, Poor speech, Psychomotor retardation, Seizure, Short stature, Simplified gyral pattern, Skeletal muscle atrophy, Strabismus, Truncal ataxia [+]
Mouse (34 sources): abnormal brain development, abnormal cone electrophysiology, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal freezing behavior, abnormal long term potentiation, abnormal retina blood vessel pattern, abnormal retina neuronal layer morphology, abnormal retina outer nuclear layer morphology, abnormal retina photoreceptor morphology, abnormal retina pigment epithelium morphology, abnormal retina vasculature morphology, abnormal rod electrophysiology, blind uterus, choroidal neovascularization, decreased body size, decreased epididymal fat pad weight, decreased retina photoreceptor cell number, decreased total retina thickness, disorganized retina inner nuclear layer, eye lesions, homeostasis/metabolism phenotype, impaired contextual conditioning behavior, impaired cued conditioning behavior, impaired synaptic plasticity, increased vascular permeability, pathological neovascularization, reduced cerebellar foliation, reduced long term potentiation, retina outer nuclear layer degeneration, retina photoreceptor degeneration, shortened ST segment, small cerebellum, thin retina outer nuclear layer [+]
View all ortholog results at Monarch