pdia6 Phenotypes

Phenotypes

XB-GENEPAGE-974679

Gene Symbol: pdia6 Gene Name: protein disulfide isomerase family A member 6

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pdia6 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal CD4-positive, CD25-positive NK T cell number, abnormal circulating cytokine level, decreased CD4-negative NK T cell number, decreased CD4-positive NK T cell number, decreased NK T cell number, decreased body size, decreased circulating insulin-like growth factor I level, decreased common lymphocyte progenitor cell number, decreased common myeloid progenitor cell number, decreased double-negative T cell number, decreased double-positive T cell number, decreased follicular B cell number, decreased hematopoietic stem cell number, decreased memory-marker CD4-positive NK T cell number, decreased pre-B cell number, decreased transitional stage B cell number, endocrine/exocrine gland phenotype, enlarged lymph nodes, hematopoietic system phenotype, immune system phenotype, increased fasting circulating glucose level, increased granulocyte monocyte progenitor cell number, increased marginal zone B cell number, increased marginal zone precursor B cell number, increased mature B cell number, increased memory-marker CD4-positive NK T cell number, preweaning lethality, complete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal CD4-positive, CD25-positive NK T cell number, abnormal circulating cytokine level, decreased CD4-negative NK T cell number, decreased CD4-positive NK T cell number, decreased NK T cell number, decreased body size, decreased circulating insulin-like growth factor I level, decreased common lymphocyte progenitor cell number, decreased common myeloid progenitor cell number, decreased double-negative T cell number, [+]