| Monarch Ortholog Phenotypes
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Human (32 sources):
Abnormal heart valve morphology,
Abnormality of the skin,
Abnormal left ventricular outflow tract morphology,
Abnormal pinna morphology,
Aortic aneurysm,
Aortic regurgitation,
Aortic valve stenosis,
Arrhythmia,
Atrial fibrillation,
Bicuspid aortic valve,
Broad forehead,
Delayed skeletal maturation,
Dental crowding,
Dolichocephaly,
High palate,
Intellectual disability,
Left ventricular outflow tract obstruction,
Long face,
Low-set ears,
Micrognathia,
Mitral valve prolapse,
Myxomatous mitral valve degeneration,
obsolete Joint hyperflexibility,
Prominent nose,
Ptosis,
Pulmonic stenosis,
Short philtrum,
Short stature,
Subvalvular aortic stenosis,
Tetralogy of Fallot,
Tricuspid regurgitation,
Ventricular septal defect
[+]
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Mouse (7 sources):
abnormal hepatocyte morphology,
abnormal vascular development,
abnormal vitelline vasculature morphology,
embryonic lethality, complete penetrance,
embryonic lethality during organogenesis, complete penetrance,
liver hemorrhage,
postnatal lethality, incomplete penetrance
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.