| Monarch Ortholog Phenotypes
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Human (17 sources):
Arterial occlusion,
Arterial thrombosis,
Cerebral venous thrombosis,
Deep venous thrombosis,
Hepatic vein thrombosis,
Mesenteric venous thrombosis,
Miscarriage,
Portal vein thrombosis,
Pregnancy exposure,
Pulmonary embolism,
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Mouse (20 sources):
abnormal atrial thrombosis,
abnormal blood coagulation,
abnormal cardiac thrombosis,
abnormal liver regeneration,
abnormal optic choroid morphology,
abnormal placental thrombosis,
abnormal retina layer morphology,
abnormal retina pigment epithelium morphology,
abnormal sclera morphology,
abnormal thrombosis,
decreased litter size,
increased susceptibility to induced thrombosis,
lethality throughout fetal growth and development, complete penetrance,
macrovesicular hepatic steatosis,
myocardial fiber degeneration,
neonatal lethality, incomplete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
preweaning lethality, complete penetrance,
venoocclusion
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.