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Summary Expression Phenotypes Gene Literature (12) GO Terms (13) Nucleotides (93) Proteins (33) Interactants (146) Wiki
XB-GENEPAGE-977138

chrna1     cholinergic receptor, nicotinic alpha 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: chrna1 assayed (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (82 sources): Abnormal cervical curvature, Abnormal facial shape, Abnormality of eye movement, Abnormality of masticatory muscle, Abnormality of the musculature of the upper limbs, Akinesia, Amyoplasia, Ankle weakness, Arthrogryposis multiplex congenita, Bulbar palsy, [+]
Mouse (7 sources): abnormal endplate potential, abnormal innervation pattern to muscle, abnormal miniature endplate potential, abnormal neuromuscular synapse morphology, carpoptosis, increased motor neuron number, preweaning lethality, complete penetrance

View all ortholog results at Monarch