taco1 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (96)

Interactants (30)

XB-GENEPAGE-986961

Gene Symbol: taco1 Gene Name: translational activator of mitochondrially encoded cytochrome c oxidase I

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (57 sources): Abnormality of movement, Acidosis, Aminoaciduria, Anemia, Apnea, Ataxia, Cytochrome C oxidase-negative muscle fibers, Decreased activity of mitochondrial respiratory chain, Decreased activity of the pyruvate dehydrogenase complex, Decreased liver function, Dysarthria, Dystonia, Emotional lability, Exercise intolerance, Exertional dyspnea, Failure to thrive, Focal T2 hyperintense basal ganglia lesion, Generalized hypotonia, Global developmental delay, Glycosuria, Hearing impairment, Hepatomegaly, High palate, Hyperphosphaturia, Hyperreflexia, Hypertrichosis, Hypertrophic cardiomyopathy, Hypotonia, Increased CSF lactate, Increased circulating lactate concentration, Increased hepatocellular lipid droplets, Increased intramyocellular lipid droplets, Intellectual disability, Intellectual disability, severe, Lactic acidosis, Leukodystrophy, Leukoencephalopathy, Motor delay, Nystagmus, Ophthalmoplegia, Optic atrophy, Peripheral neuropathy, Pigmentary retinopathy, Progressive cerebellar ataxia, Progressive spastic paraplegia, Proteinuria, Ptosis, Renal Fanconi syndrome, Renal tubular dysfunction, Respiratory distress, Respiratory insufficiency due to muscle weakness, Seizure, Sensorineural hearing impairment, Spasticity, Strabismus, Ventricular septal defect, Weakness of facial musculature [+]
Mouse (16 sources): Purkinje cell degeneration, abnormal heart weight, abnormal respiratory electron transport chain, cardiac hypertrophy, decreased retina inner nuclear layer thickness, grizzled coat color, increased astrocyte number, increased astrocyte size, increased grip strength, increased heart weight, premature aging, preweaning lethality, incomplete penetrance, ruffled hair, thick interventricular septum, thick ventricular wall, thin retina outer plexiform layer [+]
View all ortholog results at Monarch