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XB-GENEPAGE-987809
cd2ap CD2-associated protein
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal apical constriction (1 source), abnormal neural plate morphology (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: cd2ap manipulated (1 source) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| neural tube defect (1AP source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + cd2ap MO2 (2 sources), Xla Wt + cd2ap MO1 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (5 sources): Focal segmental glomerulosclerosis, Hematuria, Hypertension, Proteinuria, Renal insufficiency |
| Mouse (11 sources): abnormal podocyte morphology, abnormal renal glomerulus morphology, decreased T cell proliferation, decreased grip strength, increased circulating creatinine level, increased mesangial cell number, increased susceptibility to injury, premature death, renal glomerulus hypertrophy, spleen atrophy, [+] |
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View all ortholog results at Monarch |