| Monarch Ortholog Phenotypes
|
|
Human (16 sources):
Abnormality of movement,
Agenesis of corpus callosum,
Bimanual synkinesia,
Cerebral palsy,
Cleft palate,
Clumsiness,
Dysgenesis of the hippocampus,
Easy fatigability,
Fused cervical vertebrae,
Hypogonadotropic hypogonadism,
[+]
|
Mouse (22 sources):
abnormal axon guidance,
abnormal brain commissure morphology,
abnormal dorsal spinal root morphology,
abnormal inner ear canal fusion,
abnormal locomotor coordination,
abnormal mammary gland development,
abnormal pontine nuclei morphology,
abnormal pyramidal decussation morphology,
abnormal righting response,
abnormal spinal cord central canal morphology,
abnormal spinal cord dorsal column morphology,
abnormal spinal cord ependymal layer morphology,
abnormal spinal cord ventral commissure morphology,
absent gastric milk in neonates,
absent hippocampal commissure,
absent lateral semicircular canal,
absent posterior semicircular canal,
hearing/vestibular/ear phenotype,
lethality throughout fetal growth and development, complete penetrance,
nervous system phenotype,
perinatal lethality, complete penetrance,
postnatal lethality, complete penetrance
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.