ptger4 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (2)

XB-GENEPAGE-992299

Gene Symbol: ptger4 Gene Name: prostaglandin E receptor 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ptger4 assayed (11 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (44 sources): abnormal Langerhans cell physiology, abnormal T cell activation, abnormal calcium ion homeostasis, abnormal cardiac muscle tissue morphology, abnormal circulating interleukin-6 level, abnormal circulating serum amyloid protein level, abnormal cytokine level, abnormal heart echocardiography feature, abnormal macrophage physiology, abnormal myocardial fiber morphology, abnormal osteoclast differentiation, abnormal osteoclast physiology, abnormal prostaglandin level, abnormal pulmonary alveolus morphology, abnormal vascular regression, cardiac hypertrophy, cardiac interstitial fibrosis, cardiovascular system phenotype, decreased T cell proliferation, decreased cardiac muscle contractility, decreased incidence of tumors by chemical induction, decreased interferon-gamma secretion, decreased pulmonary vascular resistance, decreased survivor rate, decreased susceptibility to induced arthritis, decreased susceptibility to type IV hypersensitivity reaction, dilated heart left ventricle, heart inflammation, homeostasis/metabolism phenotype, immune system phenotype, increased heart weight, increased lung weight, left-to-right shunt, liver vascular congestion, lung hemorrhage, macrovesicular hepatic steatosis, microvesicular hepatic steatosis, no abnormal phenotype detected, postnatal lethality, postnatal lethality, complete penetrance, preneoplasia, pulmonary alveolar hemorrhage, pulmonary vascular congestion, thin ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (44 sources): abnormal Langerhans cell physiology, abnormal T cell activation, abnormal calcium ion homeostasis, abnormal cardiac muscle tissue morphology, abnormal circulating interleukin-6 level, abnormal circulating serum amyloid protein level, abnormal cytokine level, abnormal heart echocardiography feature, abnormal macrophage physiology, abnormal myocardial fiber morphology, [+]