ikzf3 Phenotypes

Phenotypes

XB-GENEPAGE-994461

Gene Symbol: ikzf3 Gene Name: IKAROS family zinc finger 3

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (2 sources): Cellular immunodeficiency, Chronic lymphatic leukemia
Mouse (27 sources): abnormal blood urea nitrogen level, abnormal spleen marginal zone morphology, abnormal type III hypersensitivity reaction, autoimmune response, decreased IgG2b level, decreased IgG3 level, decreased large unstained cell number, decreased marginal zone B cell number, decreased naive B cell number, increased anti-double stranded DNA antibody level, increased anti-histone antibody level, increased anti-nuclear antigen antibody level, increased anti-single stranded DNA antibody level, increased autoantibody level, increased B cell derived lymphoma incidence, increased B cell proliferation, increased circulating creatinine level, increased follicular B cell number, increased grip strength, increased IgG1 level, increased IgG2a level, increased neutrophil cell number, increased pre-B cell number, increased spleen germinal center number, increased T cell proliferation, premature death, renal glomerular immunoglobulin deposits [+]
View all ortholog results at Monarch