| Monarch Ortholog Phenotypes
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Human (32 sources):
Abdominal distention,
Anemia,
Cholestasis,
Cirrhosis,
Decreased liver function,
Delayed gross motor development,
Delayed speech and language development,
Elevated circulating hepatic transaminase concentration,
Esophageal varix,
Fasting hypoglycemia,
Fatigable weakness of skeletal muscles,
Fatigue,
Growth delay,
Hepatic fibrosis,
Hepatic steatosis,
Hepatocellular adenoma,
Hepatomegaly,
Hypercholesterolemia,
Hyperlipidemia,
Hypertriglyceridemia,
Hyperuricemia,
Hypoglycemia,
Hypoglycemic seizures,
Hypotonia,
Infantile muscular hypotonia,
Intellectual disability,
Ketosis,
Lactic acidosis,
Motor delay,
Short stature,
Skeletal muscle atrophy,
Splenomegaly
[+]
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Mouse (1 source):
increased lean body mass
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.