piga Phenotypes

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Phenotypes

Gene Literature (4)

Nucleotides (115)

Interactants (151)

XB-GENEPAGE-996764

Gene Symbol: piga Gene Name: phosphatidylinositol glycan anchor biosynthesis class A

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (93 sources): Abdominal pain, Abnormal bleeding, Abnormal cerebral white matter morphology, Abnormality of skin pigmentation, Abnormality of the nervous system, Abnormal pons morphology, Abnormal renal physiology, Abnormal skin morphology, Abnormal thrombosis, Absent septum pellucidum, Absent speech, Acute myeloid leukemia, Angina pectoris, Anteverted nares, Aplastic anemia, Atrial septal defect, Axial hypotonia, Birth length greater than 97th percentile, Bone marrow hypocellularity, Cerebellar hypoplasia, Cerebral artery stenosis, Cerebral cortical atrophy, Cerebral visual impairment, Cirrhosis, Coarse facial features, Delayed myelination, Depressed nasal bridge, Developmental regression, Downturned corners of mouth, Duplicated collecting system, Dysphagia, Elevated circulating alkaline phosphatase concentration, Elevated hepatic iron concentration, Epileptic encephalopathy, Fatigue, Flexion contracture, Generalized myoclonic seizure, Gingival overgrowth, Gliosis, Global developmental delay, Hearing impairment, Hemoglobinuria, Hemolytic anemia, Hepatomegaly, High palate, Hydrops fetalis, Hypercoagulability, Hyperreflexia, Hypertelorism, Hypoplasia of the corpus callosum, Hypoplastic anemia, Hypsarrhythmia, Ichthyosis, Increased head circumference, Infantile spasms, Large fontanelles, Large for gestational age, Lower limb spasticity, Macrocephaly, Malar flattening, Microcephaly, Microdontia, Micrognathia, Micropenis, Muscle weakness, Myelodysplasia, Myocardial infarction, Myoclonus, Narrow mouth, Neuronal loss in central nervous system, obsolete Central hypotonia, Olfactory lobe agenesis, Overfolded helix, Overgrowth, Pallor, Pancytopenia, Paroxysmal nocturnal hemoglobinuria, Polyhydramnios, Prominent occiput, Pulmonary arterial hypertension, Pulmonary embolism, Seborrheic dermatitis, Secondary microcephaly, Short neck, Small nail, Spasticity, Thromboembolism, Transient ischemic attack, Triangular mouth, Upper limb spasticity, Upslanted palpebral fissure, Vesicoureteral reflux, Widely spaced teeth [+]
Mouse (27 sources): abnormal amino acid level, abnormal brain development, abnormal cartilage development, abnormal craniofacial bone morphology, abnormal definitive hematopoiesis, abnormal epidermal lamellar body morphology, abnormal epidermis stratum corneum morphology, abnormal gametes, abnormal plasma membrane morphology, abnormal suckling behavior, abnormal T cell activation, abnormal visceral yolk sac morphology, acanthosis, craniofacial phenotype, decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, decreased embryo size, decreased locomotor activity, failure of sperm-egg fusion, impaired fertilization, impaired skin barrier function, increased B cell derived lymphoma incidence, increased erythrocyte osmotic fragility, increased hemangioma incidence, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, prenatal lethality, complete penetrance, weakness [+]
View all ortholog results at Monarch