Hypoalbuminemia, Hypoglycemia, Hypogonadism, Hypothyroidism, Ichthyosis, Lymphopenia, Mental deterioration, Microcephaly, Micropenis, Nephrotic syndrome, Peripheral neuropathy, Proteinuria, Ptosis, Seizure, Sensorineural hearing impairment, Stage 5 chronic kidney disease, Strabismus

abnormal myocardial fiber morphology, abnormal neurocranium morphology, abnormal osteoclast morphology, abnormal palatal shelf fusion at midline, abnormal postnatal growth, abnormal pulmonary alveolus morphology, abnormal regulatory T cell number, abnormal renal glomerulus morphology, abnormal renal/urinary system morphology, abnormal smooth muscle morphology, abnormal spermatid morphology, abnormal spermatocyte morphology, abnormal spleen periarteriolar lymphoid sheath morphology, abnormal sternum morphology, abnormal testis cord formation, abnormal thymus lobule morphology, abnormal type IV hypersensitivity reaction, abnormal urinary bladder urothelium morphology, abnormal urothelium morphology, abnormal vascular smooth muscle morphology, abnormal vertebral arch morphology, absent corpus luteum, absent podocyte slit diaphragm, anovulation, asymmetric sternocostal joints, cardiovascular system phenotype, decreased CD4-positive, alpha beta T cell number, decreased Leydig cell number, decreased circulating estradiol level, decreased double-positive T cell number, decreased erythrocyte cell number, decreased fibroblast cell migration, decreased follicular B cell number, decreased hematocrit, decreased hemoglobin content, decreased marginal zone B cell number, decreased palatine bone horizontal plate size, decreased pre-B cell number, decreased single-positive T cell number, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased tertiary ovarian follicle number, decreased theca cell number, growth/size/body region phenotype, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased granulocyte number, increased osteoclast cell number, increased single-positive T cell number, increased thymocyte number, increased vertical activity, lymphoid hypoplasia, multinucleated giant male germ cells, no abnormal phenotype detected, pale kidney, podocyte foot process effacement, polychromatophilia, postnatal lethality, premature death, preweaning lethality, complete penetrance, respiratory system phenotype, small kidney, small ovary, small presphenoid bone, thick pulmonary interalveolar septum, thymus cortex hypoplasia, thymus medulla hyperplasia