| Monarch Ortholog Phenotypes
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Human (35 sources):
Abnormal eye physiology,
Abnormal internal carotid artery morphology,
Abnormal left ventricular function,
Abnormal nervous system physiology,
Abnormal tendon morphology,
Angina pectoris,
Aortic atherosclerotic lesion,
Arthralgia,
Calcification of the aorta,
Cerebral artery atherosclerosis,
Corneal arcus,
Coronary artery aneurysm,
Coronary artery atherosclerosis,
Dyspnea,
Heart murmur,
Hepatic steatosis,
Hypercholesterolemia,
Hyperlipidemia,
Hypertension,
Increased LDL cholesterol concentration,
Mitral regurgitation,
Myocardial infarction,
Myocardial steatosis,
Optic neuropathy,
Peripheral arterial stenosis,
Precocious atherosclerosis,
Premature arteriosclerosis,
Premature coronary artery atherosclerosis,
Renal artery stenosis,
Renal steatosis,
Sudden cardiac death,
Supravalvular aortic stenosis,
Tendon xanthomatosis,
Xanthelasma,
Xanthomatosis
[+]
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Mouse (8 sources):
abnormal circulating alkaline phosphatase level,
abnormal circulating cholesterol level,
abnormal circulating triglyceride level,
abnormal liver regeneration,
homeostasis/metabolism phenotype,
impaired liver regeneration,
increased bile salt level,
increased circulating alkaline phosphatase level
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.