pola1 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-1000547

[provisional- machine annotated only]

Gene Symbol: pola1 [Predicted: Source is Human Entrez Gene]

Gene Name: polymerase (DNA directed), alpha 1, catalytic subunit [Predicted: Source is Human Entrez Gene]

Synonyms: pola, DNA polymerase alpha Add Xenopus synonyms

Gene Function: DNA polymerase alpha, catalytic subunit

Interactants: cdc45(9) , pcna(9) , rpa1(5) , mcm10(4) , cdk2(3) , mcm3(3) , polg(3) View All

XB-GENE-1000548

XB-GENE-1000552

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1
	Entrez Gene	Entrez Gene
mRNA	NCBI Nucleotide >XM_002933612\|PREDICTED: Xenopus (Silurana) tropicalis polymerase (DNA directed), alpha 1, catalytic subunit (pola1), mRNA GAGACTTGTGACGTCAGGGCTAGCTGTCTGGCGCTTGCGGGAACTTTAAGCAGCAGCCCGGGATTCTCCCGCGAAAAAGTAGCATTGTCGGTAGACATGTCAGAATCTGGAAGTTTTGCAGCATCACGTTCGCGGCGTGAAAAAACAGAAAAGAGCGGCCGTAAAGAAGCATTGGAACGTTTGAAAAGAGCAAAAGCTGGTGAAAAAGTCAAATATGAGGTGGAAGAAATTTCAAGCATTTATGAGGAGGTGGATGAAGAACAATACTCTAAAATTGTTCGTGACCGACAGGATGATGATTGGATAGTGGATGATGATGGGACCGGTTATGTAGAAGATGGAAGAGAGATTTTTGATGATGACTTAGAAGACAATGCTCTTGCTGATTCAGGTAAAAGAGCTAAGGGAGCACCCAAAGATAAATCTAATGTAAAAAAGTCATCGGTGTCGAAGCCAAATAATATCAAGTCAATGTTTATGGCCAGTGCTGTCAAAAGGACAACAGATAAAACTGTGGATCTGTCAAAAGATGACTTGCTTGGTGATTTACTGCAAGATTTAAAGTCACAGGCTCTTCCTATAACACCACCCCCAGTAATTACTCTAAAGAAGAAGAAACTTGCAGGGTCTCCTTTAAACCCTTTCTCGGTACCACCTGCTGCCCCAAAGGTTTTACCTGTGAAAAAACCACCAGCTTTAGCAAAGCTTGGGCATCTCTCAAGTGCTGCGCCATCTAACAACTCTGCCAGTTCTTTTGTACCCCGGGAAATTAAGAATGAGCCAAATTCTGATTTGATTTCTTCTGCTCCTTTGAATGTGAAAACTCAAGTAAAAGAAGAGGATACGTCAATGGTTGAGTTCGATGATGGAGATTTTGATGAACCAATGGAAGAAGACAATTTGGAATCTCCTTCAGTTGTTTCTAGCACAATTAAGAAGGAAGAACCAAAAATTAAGTGTGTGAAAGAGGATAGTGTTAAAATGGAGGAAAGTTCTTTCATGACTTCCGCTGCTTTAAATGAATCTTGTTGGGATCAAATTGATGAGGTTGAATCAATGACCACTGAAGTTCAGGTAGATTCAAGCCGCCTACCCTTGGTTACAGGTGCAGATGGAAGTCAGGTGTTTAAGTTTTATTGGCTAGATGCCTATGAAGACCAGTACAGTCAGCCAGGAGTAGTCTACTTATTTGGAAAAGTTTGGATAGAGACAGCTGAGGCGTATGTCAGCTGCTGTGTTAGTGTGAAGAACATTGAGAGGACTGTATATCTCCTACCTCGTGAAAATAGAGTGCAGCTTTCTACAGGCAAAGACACTGGAGTACCAGTGTCTATGATGAATGTATACCAGGAGTTTAATGAAAGTGTTGCAGAAAAGTACAAAATCATGAAGTTCAAGTCTAAGAAAGTTGAGAAGGATTATGCTTTTGAAATTCCTGATGTTCCAGCCAGCTCTGAATATCTAGAGGTTCGATATTCTGCGGACTCACCTCAACTTCCTCAGGATCTAAAAGGAGAAACATTTTCACATGTGTTTGGAACAAATACTTCAAGCCTGGAGCTTTTCTTGCTTAGCAGAAAAATAAAAGGGCCCAGCTGGCTGGAGATAAAAAGCCCACAGCTGAGCAGTCAGCCCATGAGCTGGTGCAAGGTTGAGGCAGTGGTGATGAGGCCTGACCAAGTGAATGTTGTGAAGGATCTGGCACCTCCACCTGTTGTTGTTTTGTCGCTCAGTATGAAGACTGTGCAGAATGCAAAGACTCACCAAAATGAGATTGTGGCAATGGCTGCTTTGGTTCATCACAAATTTCCCTTTGATAAAGCACCACCACAGCCACCATTCCAGACACATTTTTGTGTTCTGAGCAAACCTAATGATTGCATTTTCCCATACGACTTTAAGGAAGCGGTGAAACGAAAGAATGCAAATATTGAGATTGCGTTAACTGAACGAACTCTACTGGGCTTTTTCCTAGCAAAAATTCATAAAATTGATCCAGATATTATTGTAGGCCATGACATTTATGGTTTTGATCTCGAAGTGTTGCTTCAAAGAATTAGCTCGTGCAAGGTTCCTTTCTGGTCCAAAATCGGTAGACTGAGAAGATCTGTTATGCCAAAACTTGGGGGTCGAAGTGGCTTTGCAGAAAGGAATGCAGCTTGTGGTCGCATCATTTGCGATACTGAGATTTCTGCCAAGGAGTTAATTCGATGTAAAAGCTATCATTTGTCAGAACTGGTACATCAAATATTGAAAACAGAGAGAGTTTTGATGCCACCAGAAAACATCCGCAATGCATACAGTGATTCAGCACATCTTCTTTACATGCTGGAGAACACCTGGACTGATGCAAAATTCATCCTTCAGATCATGTGTGAGCTGAATGTTCTTCCCCTGGCCTTGCAGATCACAAATATTGCAGGCAATGTCTTGTCAAGGACATTAATGGGTGGACGCTCAGAAAGAAACGAGTACCTTCTCCTTCATGCCTTCACAGAAAATAACTTCATAGTGCCAGACAAGCCAGTGTTCAAGAAAATTCAACAGACCACTGTGGAGGACGATGATAATATGGACACAGATCAAAATAAAAATAAGAAAGGTCGAAAGAAGGCTGCCTATGCTGGAGGATTGGTCCTGGAACCCAAAGTTGGTTTCTACGACAAATTCATCTTGCTTCTGGATTTCAACAGCTTGTACCCCTCTATCATTCAGGAATATAATATCTGCTTTACAACAGTGCAAAGAGAGGCTCCTACTTCACAGAAAGGTGAAGATCAGGAAGAAATTCCAGAGCTACCTCATTCTGATCTTGAAATGGGGATCTTACCACGAGAGATACGGAAACTGGTGGAGAGGAGGCGTCACGTGAAGCAGTTAATGAAGCAGCCTGACCTAAACCCTGATTTATACTTACAGTATGACATCAGACAAAAAGCTTTAAAGCTCACGGCAAACAGCATGTATGGATGCCTGGGCTTCTCCTACAGCAGGTTCTATGCCAAACCTTTGGCTGCATTGGTTACTCACCAAGGGAGAGAGATTTTGCTGCATACCAAGGAAATGGTACAGAAGATGAATCTGGAAGTCATATATGGAGACACGGATTCTATCATGATAAACACCAATTGTAATAATTTAGAAGAAGTCTTCAAGCTTGGAAACCGGGTGAAAAGTGAGGTAAACAAATCATACAAACTTTTAGAGATTGACATTGATGGTATCTTTAAATCACTCTTGCTACTTAAGAAAAAGAAGTATGCCGCTCTGACTGTGGAGCCTACAGGTGATGGAAAGTATGTTACTAAGCAGGAGCTTAAAGGTTTGGATATTGTCAGAAGAGACTGGTGTGAACTTGCTAAAGAAGCTGGAAATTATGTTATCAGTCAGATTCTGTCTGATCAGCCACGTGACAATATTGTTGAGAACATTCAGAAGAAATTAACTGAAATTGGGGAGAATGTAACAAATGGAACTGTGCCCATTAGCCAGTATGAAATAAACAAGGCATTGACAAAGGATCCTCAGGATTACCCTGATAAAAAAAGCTTACCTCACGTACATGTTGCCATGTGGATAAATTCCCAAGGTGGAAGAAAGGTGAAAGCTGGTGATACAATATCCTATGTCATTTGCCAGGACGGATCAAATCTTAGTGCCAGCCAGAGAGCATATGCTCCAGAGCAGCTGCAAAAACAAGAGAACCTTTCCATTGACACACAATACTACCTGTCACAGCAAGTCCACCCAGTAGTGGCTCGGATCTGTGAGCCCATTGATGGAATTGATTCTGCACTCATTGCAATGTGGTTAGGACTTGACCCCTCCCAGTTCCGGGCTCACCGCCACCATCAGCAGGATGAGGAAAATGATGCATTGTTGGGAGGTCCTTCCCAACTCACAGATGAGGAAAAATACAGAGATTGTGAACGATTCAAATTCTTCTGCCCAAAGTGTGGAACAGAGAACATTTATGACAATGTTTTTGATGGCTCTGGGCTGCAGATTGAACCCGGCTTGAAACGCTGCAGTAAACCAGAGTGTGATGCTTCTCCCTTGGACTACGTTATTCAGGTTCAAAACAAGCTGCTCTTGGACATAAGACGTTACATAAAGAAATACTACAGTGGTTGGCTTGTATGTGAAGAAAAAACCTGCCAGAACAGAACACGACGAGTTCCTCTGAGCTTCTCCCGCAATGGGCCGATATGCCAAGCTTGCACTAAAGCAACGCTAAGATCAGAGTATCCGGAAAAGGCCCTGTACACTCAGCTTTGTTTCTATAGATTCATTTTTGACTGGGATTATGCACTGGAGAAAGTTGTTTCTGAACAAGAGAGAGGTCACTTAAAAAAGAAGCATTTTCAAGAGTCAGAAAATCTGTACAAGAAGTTAAAGAGCACTGTCGACCAAGTACTTTCACAGAGCGGGTATTCAGAAGTGAACCTCAGCAAGCTGTTCCAAACACTCAGCACCATTAAATAACCACTAGTTTCTCTCAATAATGTAATCTGTTAGGGCCTTATTTGTTAGTTTTACTTTGTTTGAAAACTTCTATTGGATTCCAGACTAAAACGTATTTTTCTCCTAGTGTAATGACATAGTGATTCCATGCCAAGGGTTTTCCATCAAGCCTTAAGAGACCCAAGGATTGCTACAAGTGATCCATAGTGTCTTGGTATTTAGTTGAGGTGCTTGTAAGAAAAGAAACCAGTAGCTCAGTAGGACGACTGTTTCTTTTCATTTCATCCGCTTCACAACAAAACCTTGCTGGTTACAAGAAAATAGGTTGAACAATTCTAAATACAAATTAAAGAGAAAACAAAAAGGTTAATATTGCTTAAATGGCCTTTTTCTGTATTGTATGTTGTAAAAATGTATTTTTAGTGTCTGTTTTCTGCTCATTAATATACTGCCAGCTATGCAGTAATATCTAAAATATTGATATTAAATATTAATACATTATGAATAGTAGTTGTGTGTGCATATATGTGATAATTGTTCTGCAGATGTATTGTTTACTCTTTATAATGTTATTGTCTTTAATAATTGTAAAGGCTTTTATACTGTTGGAGCATCAAAATAAAGCTATTTACTGGAACA	Refseq >NM_001088586\|Xenopus laevis polymerase (DNA directed), alpha 1, catalytic subunit (pola1), mRNA TAGCTGTCTGGCGCTTGCGGGAAGTTCAAGCGAGCGCTCTGTGACTGTCCCGCGAAAAGTGGAAGTGTTGGGCGACATGTCAGACTCCGGAAGTTTCGCTGCATCTCGTTCACGGCGGGAAAAAACAGAAAAGTCGGGCCGCAAGGAAGCTTTGGAACGCTTGAAAAGAGCAAAGGCTGGTGAAAAAGTCAAATATGAGGTGGAGCAAGTGTCCAGCATTTATGAAGAGGTTGATGAAGCAGAATACTCTAAGCTTGTCCGTGACCGTCAGGATGATGATTGGATAGTAGATGATGATGGGACTGGCTACGTAGAAGATGGAAGAGAGATTTTTGATGATGACTTAGAAGACAATGCCCTTGCTGATTCAGGTAAAGGCGCTAAGGGAGCACCCAAAGACAAAACAAATGTAAAAAAGTCATCGGTGTCCAAGCCAAATAATATCAAGTCCATGTTTATGGCCAGTGCTGTGAAAAAGACAACAGATAAAGCTGTGGATTTGTCAAAAGATGATTTGCTTGGAGATTTATTGCAAGATTTGAAGTCGCAGGCTGTTCCTATAACACCACCACCAGTAATTACACTAAAGAAGAAGAAACTTGCAGGATCTCCTTTAAACCCTTTCTCAGTACCACCTACAGCCCCAAAGGTTTTACCTACAAGTGTGAAAAGATTACCAGCTGTAACCAAGCCTGGGCATCCTGCTGCACAATCAAAGGCTTCTGTACCCCGGCAAATAAAGAAAGAGCCTAAGGCTGAGTTGATTTCTTCTGCTGTTGGTCCTTTGAAAGTGGAAGCTCAAGTAAAAGAAGAGGATTCGGGAATGGTTGAGTTTGATGATGGAGATTTTGATGAACCCATGGAAGAAGATGTGGAAATAACTCCAGTTGATTCTAGCACAATCAAGACACAAGCACAAAGCATTAAGTGTGTGAAAGAGGAAAATATTAAAGAGGAAAAAAGTTCATTCATAACTTCTGCTACTTTAAATGAGTCTTGTTGGGATCAAATTGATGAGGCTGAACCAATGACCACTGAAATTCAGGTAGATTCAAGCCACCTACCCTTGGTTACTGGTGCAGACGGGAGTCAAGTTTTTAGGTTTTATTGGCTAGATGCCTATGAAGACCAGTACAGTCAGCCAGGAGTAGTCTATTTGTTTGGAAAAGTTTGGATCGAGTCAGCTGATGCATATGTCAGCTGCTGTGTTAGTGTGAAGAACATTGAGAGGACCGTATATCTTCTACCTCGTGAAAATAGAGTGCAGCTTTCAACAGGAAAAGACACTGGAGCACCAGTTTCTATGATGCATGTATATCAGGAGTTTAATGAGGCTGTTGCAGAAAAGTACAAAATCATGAAGTTTAAATCCAAGAAAGTTGATAAGGATTACGCTTTTGAAATACCTGATGTTCCAGCAAGCTCTGAATATCTGGAGGTTCGATATTCTGCGGACTCACCCCAACTTCCTCAGGATCTAAAAGGAGAAACATTTTCACATGTTTTTGGAACAAATACTTCAAGCTTGGAGCTTTTCTTGCTTAGCAGAAAAATAAAAGGGCCCAGCTGGCTGGAGATAAAAAGCCCACAACTGTCCAGTCAGCCCATGAGCTGGTGCAAGGTTGAGGCAGTGGTGACGAGGCCTGACCAAGTGAGCGTTGTGAAGGATCTCGCACCTCCTCCTGTCGTTGTTTTATCTCTCAGTATGAAGACCGTGCAGAATGCAAAGACTCACCAAAATGAGATTGTGGCAATAGCTGCTTTGGTTCATCACACATTTCCTCTTGATAAGGCACCACCCCAGCCACCTTTCCAAACTCATTTTTGTGTTCTGAGCAAACTTAATGACTGCATTTTCCCATATGACTACAATGAAGCAGTGAAACAAAAGAATGCCAATATTGAGATTGCGTTAACTGAACGAACTCTACTTGGGTTTTTCCTAGCAAAAATTCATAAAATTGATCCAGATGTTATTGTAGGCCATGACATTTATGGTTTTGATCTTGAAGTGCTGCTTCAAAGGATTAACTCATGCAAGGTTCCATTCTGGTCCAAAATTGGGAGACTGAGAAGATCTGTTATGCCAAAACTTGGGGGTCGAAGTGGCTTTGCAGAAAGAAATGCAGCTTGTGGACGCATAATTTGTGATATTGAGATTTCTGCCAAGGAGTTAATTCGCTGTAAAAGCTATCATTTGTCTGAATTGGTACATCAGATACTGAAAGCAGAGAGAGTTGTAATCCCACCTGAAAACATCCGCAATGCATATAATGATTCAGTACATCTTCTGTACATGCTGGAGAACACCTGGATTGATGCAAAATTCATCCTTCAGATCATGTGTGAGCTGAATGTTCTTCCCCTGGCCTTACAAATCACAAATATTGCAGGCAATGTCATGTCAAGGACATTAATGGGTGGACGCTCAGAAAGAAACGAGTACCTACTGCTTCACGCCTTCACAGAAAATAACTTCATAGTGCCAGACAAACCAGTGTTCAAGAAAATGCAGCAGACCACTGTGGAGGACAATGATGATATGGGCACGGATCAAAATAAAAATAAGAGTCGAAAGAAAGCTGCCTATGCTGGAGGGTTGGTCCTGGAACCCAAAGTGGGTTTCTATGACAAATTCATCTTGCTTCTCGATTTCAACAGTTTGTACCCCTCCATCATTCAGGAATACAATATCTGCTTTACTACAGTGCACAGAGAGGCTCCCTCAACACAGAAAGGTGAAGATCAGGACGAAATTCCAGAGCTACCTCATTCCGATCTTGAAATGGGGATCTTGCCTCGAGAGATACGGAAACTGGTGGAGAGGAGGCGTCACGTGAAGCAGTTAATGAAGCAGCCTGACCTAAACCCTGATTTATACTTGCAGTATGACATCAGACAAAAAGCTCTGAAGCTCACAGCAAATAGCATGTACGGATGCCTGGGCTTTTCCTACAGCAGGTTTTATGCCAAACCTTTGGCTGCGTTGGTTACTCACCAAGGGAGAGAGATTTTGCTGCATACCAAGGAAATGGTACAAAAGATGAATCTGGAAGTCATATATGGAGACACCGATTCTATCATGATAAACACTAATTGTAATAATTTAGAAGAAGTCTTCAAGCTCGGAAACCGGGTAAAAAGTGAGATAAACAAATCATACAAGCTGTTGGAGATTGACATTGATGGTATCTTTAAATCTCTCTTGCTACTGAAGAAAAAGAAGTATGCCGCTCTTACAGTGGAGCCCACAGGTGATGGAAAGTATGTTACTAAGCAGGAGCTTAAAGGTCTTGATATTGTCAGAAGAGACTGGTGCGAGCTTGCTAAACAAGCTGGAAATTATGTTATTAGTCAGATTCTCTCTGACCAGCCGCGTGATAGTATTGTTGAAAACATTCAGAAGAAATTAACTGAAATTGGGGAAAATGTAACAAATGGAACTGTGCCCATCACCCAGTATGAAATCAATAAGGCATTGACAAAGGATCCTCAGGATTACCCTGATAAAAAAAGCTTACCCCATGTACATGTTGCCTTGTGGATAAATTCCCAAGGTGGAAGAAAGGTGAAAGCTGGCGATACAATATCCTATGTCATTTGTCAGGACGGATCAAATCTTAGTGCGAGTCAGAGAGCATATGCCCAAGAGCAGCTGCAAAAACAAGAGAACCTTTCCATTGACACACAATACTACCTGTCACAGCAAGTCCACCCAGTAGTGGCTCGGATCTGTGAGCCCATTGATGGAATTGATTCTGCACTAATTGCAATGTGGTTAGGACTTGACCCTTCCCAGTTCCGGGCTCACCGGCACTACCAGCAGGACGAGGAAAATGATGCATTGCTGGGAGGTCCTTCCCAACTCACAGATGAGGAAAAATACAGAGACTGTGAACGGTTCAAATTCTTCTGCCCAAAGTGTGGAACGGAGAACATTTATGACAATGTTTTTGATGGCTCTGGACTGCAGATTGAACCGGGCTTGAAGCGCTGCAGTAAACCAGAGTGTGATGCTTCTCCCTTGGACTATGTTATTCAGGTTCACAACAAGCTGCTCCTGGACATAAGACGATACATAAAGAAATACTACAGTGGTTGGCTGGTTTGTGAAGAAAAAACCTGCCAGAACAGAACACGGCGTCTTCCACTAAGTTTCTCCCGCAATGGGCCAATATGCCAAGCTTGTTCTAAAGCAACCCTTAGATCAGAGTATCCAGAAAAGGCCTTGTACACTCAGCTTTGTTTCTATCGATTTATTTTTGACTGGGATTATGCACTGGAGAAAGTCGTGTCTGAACAAGAGAGAGGTCACTTAAAAAAGAAGCTTTTTCAAGAATCTGAAAACCAGTACAAGAAGTTAAAGAGCACCGTTGACCAAGTACTTTCCCGGAGCGGATATTCAGAAGTGAACCTCAGCAAGCTGTTCCAGACACTCAACACCATTAAATAACCAGCAGATTTACTGAATAATGTCCTCTATTAGAGCAAGAGTAATTAAACCTGACCCTGCAAGCCAACCTGACATTCAAGCATTTTGTTATTTGCCATTGTCTGATGCGAATAGGAGGAACATTTTAAAGGTCTTGAGGTGAATGAATGCCTTTAATAAATATTGTGAAGTCAATT
Protein	NCBI Protein >XP_002933658\|PREDICTED: DNA polymerase alpha catalytic subunit [Xenopus (Silurana) tropicalis] MSESGSFAASRSRREKTEKSGRKEALERLKRAKAGEKVKYEVEEISSIYEEVDEEQYSKIVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKRAKGAPKDKSNVKKSSVSKPNNIKSMFMASAVKRTTDKTVDLSKDDLLGDLLQDLKSQALPITPPPVITLKKKKLAGSPLNPFSVPPAAPKVLPVKKPPALAKLGHLSSAAPSNNSASSFVPREIKNEPNSDLISSAPLNVKTQVKEEDTSMVEFDDGDFDEPMEEDNLESPSVVSSTIKKEEPKIKCVKEDSVKMEESSFMTSAALNESCWDQIDEVESMTTEVQVDSSRLPLVTGADGSQVFKFYWLDAYEDQYSQPGVVYLFGKVWIETAEAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGVPVSMMNVYQEFNESVAEKYKIMKFKSKKVEKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVMRPDQVNVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAMAALVHHKFPFDKAPPQPPFQTHFCVLSKPNDCIFPYDFKEAVKRKNANIEIALTERTLLGFFLAKIHKIDPDIIVGHDIYGFDLEVLLQRISSCKVPFWSKIGRLRRSVMPKLGGRSGFAERNAACGRIICDTEISAKELIRCKSYHLSELVHQILKTERVLMPPENIRNAYSDSAHLLYMLENTWTDAKFILQIMCELNVLPLALQITNIAGNVLSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKIQQTTVEDDDNMDTDQNKNKKGRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVQREAPTSQKGEDQEEIPELPHSDLEMGILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQKMNLEVIYGDTDSIMINTNCNNLEEVFKLGNRVKSEVNKSYKLLEIDIDGIFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVRRDWCELAKEAGNYVISQILSDQPRDNIVENIQKKLTEIGENVTNGTVPISQYEINKALTKDPQDYPDKKSLPHVHVAMWINSQGGRKVKAGDTISYVICQDGSNLSASQRAYAPEQLQKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHHQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIEPGLKRCSKPECDASPLDYVIQVQNKLLLDIRRYIKKYYSGWLVCEEKTCQNRTRRVPLSFSRNGPICQACTKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKHFQESENLYKKLKSTVDQVLSQSGYSEVNLSKLFQTLSTIK	Refseq >NP_001082055\|DNA polymerase alpha catalytic subunit [Xenopus laevis] MSDSGSFAASRSRREKTEKSGRKEALERLKRAKAGEKVKYEVEQVSSIYEEVDEAEYSKLVRDRQDDDWIVDDDGTGYVEDGREIFDDDLEDNALADSGKGAKGAPKDKTNVKKSSVSKPNNIKSMFMASAVKKTTDKAVDLSKDDLLGDLLQDLKSQAVPITPPPVITLKKKKLAGSPLNPFSVPPTAPKVLPTSVKRLPAVTKPGHPAAQSKASVPRQIKKEPKAELISSAVGPLKVEAQVKEEDSGMVEFDDGDFDEPMEEDVEITPVDSSTIKTQAQSIKCVKEENIKEEKSSFITSATLNESCWDQIDEAEPMTTEIQVDSSHLPLVTGADGSQVFRFYWLDAYEDQYSQPGVVYLFGKVWIESADAYVSCCVSVKNIERTVYLLPRENRVQLSTGKDTGAPVSMMHVYQEFNEAVAEKYKIMKFKSKKVDKDYAFEIPDVPASSEYLEVRYSADSPQLPQDLKGETFSHVFGTNTSSLELFLLSRKIKGPSWLEIKSPQLSSQPMSWCKVEAVVTRPDQVSVVKDLAPPPVVVLSLSMKTVQNAKTHQNEIVAIAALVHHTFPLDKAPPQPPFQTHFCVLSKLNDCIFPYDYNEAVKQKNANIEIALTERTLLGFFLAKIHKIDPDVIVGHDIYGFDLEVLLQRINSCKVPFWSKIGRLRRSVMPKLGGRSGFAERNAACGRIICDIEISAKELIRCKSYHLSELVHQILKAERVVIPPENIRNAYNDSVHLLYMLENTWIDAKFILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFTENNFIVPDKPVFKKMQQTTVEDNDDMGTDQNKNKSRKKAAYAGGLVLEPKVGFYDKFILLLDFNSLYPSIIQEYNICFTTVHREAPSTQKGEDQDEIPELPHSDLEMGILPREIRKLVERRRHVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTHQGREILLHTKEMVQKMNLEVIYGDTDSIMINTNCNNLEEVFKLGNRVKSEINKSYKLLEIDIDGIFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVRRDWCELAKQAGNYVISQILSDQPRDSIVENIQKKLTEIGENVTNGTVPITQYEINKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTISYVICQDGSNLSASQRAYAQEQLQKQENLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHYQQDEENDALLGGPSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIEPGLKRCSKPECDASPLDYVIQVHNKLLLDIRRYIKKYYSGWLVCEEKTCQNRTRRLPLSFSRNGPICQACSKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKLFQESENQYKKLKSTVDQVLSRSGYSEVNLSKLFQTLNTIK UniProtKB

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC

Synteny	Metazome

Expression	tropicalis	laevis
UniGene		Xl.7596
Unigene EST Profile		EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	POLA1
mouse	MGI	Pola1	All(2) Targeted, other(1) Gene Trapped(1)
zebrafish	ZFIN	pola1	4 Lines(s)

Publications
First:		Nuclear localization of DNA polymerase alpha in Xenopus laevis oocytes. [Biochem Biophys Res Commun 1976]
Most recent:		A large scale screen for neural stem cell markers in Xenopus retina. [Dev Neurobiol 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		3'-5' exonuclease activity DNA binding DNA-directed DNA polymerase activity More[+] alpha DNA polymerase activity beta DNA polymerase activity delta DNA polymerase activity epsilon DNA polymerase activity eta DNA polymerase activity gamma DNA-directed DNA polymerase activity iota DNA polymerase activity kappa DNA polymerase activity lambda DNA polymerase activity mu DNA polymerase activity nu DNA polymerase activity nucleotide binding sigma DNA polymerase activity theta DNA polymerase activity zeta DNA polymerase activity
Biological:		DNA replication
Cellular Component:		nucleus
EC:		DNA-directed DNA polymerase
KOG:		[L] DNA polymerase alpha, catalytic subunit

Reagents	tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0	Str.22359.1.S1_at [+] Str.46145.1.A1_at	Xl.7596.1.S1_at
Affymetrix 2.0		Xl2.7596.1.S1_a_at

Symbol legend[+]