atp2a2 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-1012932

[provisional- machine annotated only]

Gene Symbol: atp2a2 [Predicted: Source is Human Entrez Gene]

Gene Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Predicted: Source is Human Entrez Gene]

Synonyms: atp2b, dar, serca2 Add Xenopus synonyms

Gene Function: Ca2+ transporting ATPase

Interactants: atp2a1(1) , atp2a3(1) , calr(1) , mecom(1) , myod1(1) , slc12a1(1) , View All

XB-GENE-1012933

XB-GENE-1012936

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	NCBI Nucleotide >XM_002944334\|PREDICTED: Xenopus (Silurana) tropicalis sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like (LOC100491645), mRNA TTCAACCAAATCTGTTTTTAATTTTAGACTAATTTGACATTTGTTGGCTGTGTTGGAATGCTGGACCCACCAAGAACAGAAGTGGCTGCCTCTGTAAAAATGTGCAGACAGGCTGGCATTAGAGTTATCATGATTACAGGCGATAACAAGGGAACTGCTGTTGCAATTTGCCGTCGCGTTGGTATCTTCCGTGAAGATGAGGATGTTTCTGAGAGAGCTTTCACTGGACGTGAATTTGATGAACTGTCCCCTGCTGCACAGAGGGACGCTTGTTTGAATGCACGCTGTTTTGCTCGTGTAGAACCTTCACATAAGTCAAAAATTGTAGAGTTCCTGCAGTCTTTTGATGAGATTACCGCCATGACTGGTGATGGTGTAAACGATGCACCTGCGCTTAAGAAAGCAGAAATTGGAATAGCCATGGGATCTGGCACTGCAGTAGCTAAAACTGCATCTGAGATGGTGCTTGCCGATGACAACTTTTCAACCATTGTGGCTGCAGTAGAGGAAGGACGTGCCATCTATAACAACATGAAGCAGTTTATTCGATACCTTATTTCCTCTAATGTGGGAGAAGTGGTTTGCATTTTTCTAACAGCCGCTCTTGGATTCCCTGAAGCTTTAATACCTGTTCAGCTTCTGTGGGTCAATTTGGTCACTGATGGCCTTCCTGCTACCGCATTGGGTTTTAACCCCCCAGACTTGGACATAATGAACAAGCCACCCCGCAATCCAAAGGAGCCACTTATCAGTGGCTGGCTTTTCTTTCGCTATCTTGCCATTGGATGTAAGTGCAATTCCTGA	Refseq >NM_001092974\|Xenopus laevis ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (atp2a1), mRNA GGATTAGGCTGTGCGACGGCTGACGGGGACAAGAGGGAGGCCGCAAACGAAGCAGGGGGACAGCTAGTTCATTGAGGAAGGAGGGTTATTTGGGCAGAAGTAAGACTCTTATTATCCTGAAGGTGTAAAGTGTAGACAGGACGACGATTAATTGATCAATTGAGCGTAGACAGTCGGCTTTCCTGTCTCATTGAAGCTCTCCGTTTGCTGCTGACAGACACCTAGCGGCTCGCAGGCTGAGCGTACAAGCTGTTGCTTTGCCAGAGAAGCATCTCTCTTCGGCCGTGCCACACAGCTGGACTCATTCGCTCTGTCTCCTCCCCTCTAATATCAGTGAGGTGATCCCGCTCCCGGCACAAAGACTTTGGTGGCCTCGTACATTGTGTGCAAGGTGGGGGGGATTGAGAGGGCGGTGAGGAGGCCAGGGAAGCAGACATGGAGAACGCGCACACCAAGACGGTGGAGGAAGTCCTGGCTCATTGCAACGTTAACGAGAGCACGGGCCTGAGTCTGGAGCAGGTGAAAAAACAAAAGGAGAGATGGGGAACGAACGAATTGCCAGCTGAAGAAGGAAAAACATTATGGGAGTTGGTGGTCGAACAATTTGAAGATTTATTAGTTAGAATTTTACTGCTTGCTGCCTGTATATCCTTTGTTTTGGCATGGTTTGAAGAAGGCGAGGAAACCATTACAGCCTTCGTAGAACCTTTTGTAATTTTACTTATATTAGTAGCAAATGCCATTGTTGGTGTATGGCAGGAAAGAAATGCAGAAAATGCTATTGAAGCCCTCAAAGAGTATGAGCCTGAAATGGGTAAAGTGTACAGACAAGACAGAAAAAGTGTCCAGCGTATTAAAGCCAGAGATATTGTACCTGGGGACATTGTTGAAGTGGCTGTTGGTGACAAGGTACCTGCTGACATACGATTAACTTCAATCAAGTCAACAACTTTACGAGTTGACCAATCTATCCTTACAGGTGAGTCCGTGTCTGTTATCAAGCACACTGACCCTGTTCCTGATCCTCGTGCAGTCAATCAGGACAAAAAGAATATGCTGTTTTCAGGTACCAACATTGCTGCTGGTAAAGCTATTGGAGTAGTTATAGCAACAGGAGTGAACACTGAAATTGGAAAGATTAGAGATGAGATGGTAGCTACTGAGCAGGAGAGAACTCCCTTACAGCAGAAACTGGATGAATTTGGCGAACAGCTTTCCAAAGTTATATCTCTGATTTGTATTGCTGTTTGGATCATCAATATTGGACACTTCAATGACCCTGTCCATGGGGGATCTTGGATTCGGGGAGCTATCTACTATTTCAAAATTGCAGTTGCCCTTGCTGTTGCTGCCATACCTGAAGGTCTGCCGGCTGTCATCACTACCTGTTTGGCTCTGGGAACCAGGAGAATGGCAAAAAAGAATGCAATTGTTCGCAGTTTGCCATCTGTAGAAACTCTTGGCTGTACATCTGTTATCTGCTCTGACAAAACTGGCACCCTAACAACTAACCAGATGTCAGTTTGCAGGATGTTTATTGTGGATAGAGTGGAAGGAGATAATTGCTTCCTGAATGAATTTAACATTACTGGTTCCACATATGCACCCATGGGAGAAGTGTTGAAAGATGACAAGCTGGTGAAATGCCACCAATATGATGGACTTGTTGAACTTGCAACAATCTGTGCCCTTTGCAATGATTCTTCTTTGGATTTTAATGAGGCTAAGGGAGTCTATGAAAAGGTTGGAGAAGCAACAGAGACTGCGCTCACATGCCTGGTTGAAAAGATGAATGTCTTTGACACTGATCTTAAAGGGCTTTCCAGAATAGAACGTGCAAATGCTTGCAACTCGGTCATAAAACAACTGATGAAGAAGGAATTTACTTTGGAGTTCTCAAGAGATAGAAAGTCCATGTCTGCATACTGTACACCAAATAAACCAAGTCGCACATCAATGAGCAAAATGTTTGTAAAGGGGGCCCCTGAAGGTTTGATTGACAGGTGCACTCACATCCGAGTTGGAAGCGTAAAAATGGCACTAACCCCTGGAATTAAGCAGAAAATTATGAGCGTCATTCGGGAGTGGGGAACTGGCAGGGACACTCTGCGCTGCCTGGCCCTAGCAACTCATGATAACCCAGCAAGAAAAGAAGAAATGAACCTAGAGGATTCTAACAATTTCATTAATTATGAGACTAATTTGACATTTGTTGGATGTGTTGGAATGCTGGACCCACCAAGAACAGAAGTGGCTGCCTCTGTAAAAATGTGCAGGCAGGCTGGCATTAGAGTCATCATGATTACAGGTGACAACAAGGGAACTGCTGTTGCAATTTGCCGTCGCGTCGGTATCTTCCGTGAAGATGATGATGTTACTGACAAAGCCTTTACTGGACGTGAATTTGATGAACTGTCCCCAGCTGCACAGAGGGACGCTTGTTTAAATGCACGCTGTTTTGCTCGTGTAGAACCTTCCCATAAGTCAAAAATTGTAGAGTTTCTGCAGTCTTTTGATGAGATCACAGCCATGACAGGTGATGGTGTAAATGATGCGCCTGCCCTTAAGAAAGCAGAAATTGGAATAGCCATGGGATCAGGCACTGCAGTAGCTAAAACTGCATCTGAAATGGTGCTGGCAGATGACAACTTTTCAACCATTGTGGCTGCTGTAGAGGAAGGTCGTGCCATCTATAACAACATGAAGCAGTTTATTCGATACCTTATTTCTTCTAACGTTGGAGAAGTGGTTTGCATATTTCTAACAGCTGCTCTTGGATTCCCTGAAGCTTTAATACCTGTTCAGCTTTTGTGGGTTAATTTGGTCACTGATGGTCTACCTGCTACTGCATTGGGCTTTAACCCCCCAGACCTGGACATAATGAACAAGCAACCCCGCAATCCAAAGGAGCCACTTATCAGTGGCTGGCTTTTCTTTCGTTATCTTGCCATTGGATGCTATGTTGGTGCTGCTACAGTCGGTGCAGCTGCATGGTGGTTTATTGCTGCTGAAGATGGGCCAAGAATTACCTTCTATCAATTGAGCCATTTCCTGCAATGCAGAGATGAAAATCCAGATTTCGAAGGTTTGGAGTGTGAAATTTTTGAGTCTCCTTATCCAATGACCATGGCTCTTTCTGTTCTTGTTACCATAGAAATGTGTAATGCATTAAACAGTCTTTCTGAAAACCAGTCATTGCTGAGAATGCCTCCGTGGGAGAACGTGTGGCTTCTGGGTTCAATCTGCTTATCCATGTCTCTTCATTTCCTCATTCTTTATGTAGAACCACTACCACTTATCTTCCAGATTACTCCACTGAACTTGATACAGTGGCTGATGGTGCTGAAACTCTCACTACCAGTTATACTTTTGGATGAGACTCTTAAATATGTTGCTCGTAACTACCTGGAACCTGGTAAAGAGTGTGAAAAGCCTGCAACCAAAACATGTTCTTTTTCAGCATGCACTGAAGGGATCTCTTGGCCGTTTGTTCTCATTACGTTGCCCTTGGTTTTCTGGCTTTACAGCACCGACACTAACCTAACTGAAATGTTTTGGTCTTGACTGACTCTTTTACGGAATGGAAATGTTTAAATTAACCAGTTCATATTTTTTATTTTTTTTTTATTTTGTTTAATGCAATTGTCTATTTCTGCTGAATTCATATGAACATAGCGCTGGTGACGGCAAGTTTGTTTTTCATAGTAGATCATCCTTTGCTTCCCCGCGCCTCCTGACCCTAAACCAGATGAGAGGCTTTCAATTTCTTTTATATACAATTCATGTTCATTGACATGTACAGAGAGCTAACACTATTTTATGCAAATATTTTTTGTAGATGGGGAAAATGCGCATGTACAGTGTTTTGTTTCATACAGTTCATTCTCATAACATGGAAGCAAAAAAGGAAATAGTCAATGGACTCTATCTGTAGAAAATTGGCAGAAGATTTAGGGAATGTGATTAAGTTGCTAAAACTCAAGCGCACGCTCTGTCTTTCTGCATGGTTTTTTGTTTTGTTTTTTTGTTTAATTCAAATCACTATGCTGTCTGTTTAAATGGTCGGTCTTAGCCATAAGCCAGTTTTTCTGCACTAAGCAGAGCACTGCTACCTCAGTCAGTATTTTGTTTTCCCACATTCCCATTTCACTGTTTGTGCTTCTCTGTTTACACCATTCAATGTAAGAGGTATGCCTATTCTTGCTTGTGCAGAAAATTCCTTTCAGGTTCAAATCTTCTTTCCAAACCCATAGCTTTTAAGGTTATTTATTTAAATGTCTAATGTATTTTATTGTAATAGACATTGTGTATTTGTTGGGTTTTTTTTTTTTTTGCCAGTGTTGCCCATATTCGGGTTTCTATGTCTCAACTAGTTGAAAATAAAACCTTTAAACAGACGGAGGAAAATATAACTTGCCGTTTGTCTTACGACCACTTTATCACCCAAGTTCCTTATTTTCTTTCAAGGATTTTTTTCTACCTACATTTTGTAATCCTAATATGTGCGTGTGAATGGCAACTTGCACTGCAGAGTTAAAGGCTGAATTTCACGTGTTTTAGTGCATACATAACCATTCATCTGCTATTCATATTATATAGCAAGTAAGTGATCTGACCTCTGTTAATCAAAGGTTAGGGACAGAACTTGACTTATAAACTGTGTGCTTTATTTTATTTTTTTTAATGTACAATCTGTAAATAGCACATGACCAAATGGACATATTGTATAGAACTATTTTTTATTTTTCAGTGACACTAATATCTATCATTCCACTGTAATTGTTAGCGCATGTTTTCAAGTTGATTTTCTTCAGCCTCCACTGTTTGTCATTAACCGTCCTAACTCTGGCGTTTTCTCTCCAATGCCTTCCAAATTCCACCAACTAAAGTGAGTATCCATTGTCTGTGTTATAACACTCCGTCTCAGCAGGTTCATGTAGTGATGCAAGAAATTACTCTCTGTATTGTTGCTAAAAATAAACAATTATGGTTCAAAAAAAAAAAAAAAAAAAAAAAAA
Protein	NCBI Protein >XP_002944380\|PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [Xenopus (Silurana) tropicalis] MLDPPRTEVAASVKMCRQAGIRVIMITGDNKGTAVAICRRVGIFREDEDVSERAFTGREFDELSPAAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCKCNS	Refseq >NP_001086443\|ATPase, Ca++ transporting, slow twitch 2 [Xenopus laevis] MENAHTKTVEEVLAHCNVNESTGLSLEQVKKQKERWGTNELPAEEGKTLWELVVEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKARDIVPGDIVEVAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAIGVVIATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIVDRVEGDNCFLNEFNITGSTYAPMGEVLKDDKLVKCHQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSAYCTPNKPSRTSMSKMFVKGAPEGLIDRCTHIRVGSVKMALTPGIKQKIMSVIREWGTGRDTLRCLALATHDNPARKEEMNLEDSNNFINYETNLTFVGCVGMLDPPRTEVAASVKMCRQAGIRVIMITGDNKGTAVAICRRVGIFREDDDVTDKAFTGREFDELSPAAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKQPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAAEDGPRITFYQLSHFLQCRDENPDFEGLECEIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENVWLLGSICLSMSLHFLILYVEPLPLIFQITPLNLIQWLMVLKLSLPVILLDETLKYVARNYLEPGKECEKPATKTCSFSACTEGISWPFVLITLPLVFWLYSTDTNLTEMFWS

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene		Xl.45269
Unigene EST Profile		EST Profile
GEO data		GEO
Images	1 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	ATP2A2	OMIM:101900 OMIM:124200
mouse	MGI	Atp2a2	All(5) Targeted, knock Out(2) Targeted, other(3)
zebrafish	ZFIN ZFIN	atp2a2a atp2a2b

Publications
First:		Differential modulation of SERCA2 isoforms by calreticulin. [J Cell Biol 1998]
Most recent:		Tissue-specific expression of Sarcoplasmic/Endoplasmic Reticulum Calcium ATPases (ATP2A/SERCA) 1, 2, 3 during Xenopus laevis development. [Gene Expr Patterns 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism calcium-transporting ATPase activity More[+] catalytic activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
Biological:		calcium ion transport cation transport metabolic process More[+] proton transport
Cellular Component:		integral to membrane membrane
EC:		Ca2+-transporting ATPase
KOG:		[P] Ca2+ transporting ATPase

Reagents	tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Xl.24467.1.S1_at
Affymetrix 2.0		Xl2.45269.2.A1_at [+] Xl2.54074.1.S1_at

Symbol legend[+]