hoxb4 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (20)

Nucleotides (70)

Interactants (73)

XB-GENEPAGE-1033881

Gene Symbol: hoxb4 Gene Name: homeobox B4 Synonyms: XHox-b4 Add Xenopus synonyms Gene Function: Transcription factor zerknullt and related HOX domain proteins Interactants: hoxb1(9) , hoxb3(7) , hoxb9(7) , hoxd1(7) , hoxc6(6) , cdx4(4) , egr2(4) View All	1/7

XB-GENE-1033882

XB-GENE-6078784

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001123015\|Xenopus (Silurana) tropicalis homeobox B4 (hoxb4), mRNA TGAAAAGAAATAAATGAGAATGAGTTCGTTTTTGATCAGCTCCAACTATGTGGATCCCAAGTTTCCGCCCTGTGAGGAGTACTCCCACACTGACTACCTGCCCAGCGGCCATTCTCCGGAGTACTACGGCGGCCAGAAGAGGGAGAGCAGTTTCCAGCATGGGGCACCCTATTCCCGATCGCTTTCCAGCAGCAGCGCACCCTATACTTCTTGCCAGGGATCTGTGCGCCAAGGCGCAAGGCTGCCGCACTCCTCTGGGCTTCTTCCTGGCGAGAAAGCGCACTTGGAATCCAGCATAACCCCCACTTCGCCTCCATCCTGCAGCCTCATAGCCTCAGACCACAAGCACCCCGACTCCCCCGGCCAGGACCCAGTGGTGTACCCCTGGATGAAGAAAGCGCACATCTCCAGGGCCAGTTCCACTTACTCTGATGGGGAGGCCAAGAGATCCCGTACTGCTTACACCAGGCAGCAAGTGCTTGAACTGGAAAAGGAGTTTCACTACAACCGCTATCTGACCCGCAGGCGCAGGGTGGAAATTGCGCACACTTTGCGCCTTTCTGAGCGACAAATTAAGATTTGGTTCCAAAACAGGAGGATGAAATGGAAGAAAGATCACAAGCTCCCCAATACCAAGATCAGGTCTAACCCTTCTGTGAACCTCCAAATTGCAGGGGGGTCCCCAAATCAGAACAAAGGGAACCCTGTCTGCCAATGACATCCCTAGGACTAAACAAAATAAACTCAACTGTTTTTGTTTCTAATTTATAAAAGGGGAGAAGAGACTTGGCTTGGCTCCCCGGCTCATCCAGGAGAAGCCTGTAGATAGATTTCAGATTTGGAGAAGATAGATCTATGTTTCATCTTTAATCACGCCAAACCCTGGCCCATTTGTCATGTTTACACTGCGGTACAAAGGCTGAACCTCATCTGACAGAACCAACGCTCATTTTAATAAATGAGGCAAAGCCTGTGTCCCCATGACTGGATCCTCTCTTTCTTTGCTTTTTGTTTGTGCTGTAGCAGTGCGTAATATGGTGCCCAAATCCATTACAATAGAGTGTTAGCTCTGAGGGGTTCAGTCTTGTAAATCTCATTGTTTCTCAGGAGTAACCTGTCACCCTCAGTTTGGGGCCTCAGATCACACCTATTTTGGGGGGCAAGCTGATCTAAAATGGGGTGTCCCAGGTTCAGGATATCATACCCAGTTAAAGCCTCTGGCACTGTAATATATATTTAAGAACAGGATCGTGTATATACCCTTATAATATACACCCCCCTCTAGTAAGTCACCCCCCTTCCCAGTCATATTTGTTTCAACGTCACTTGGATTATGCTTTTACCTGTGTACATAGTTTACCAATAATAAAATTATTTTTCCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001096264\|Xenopus laevis homeobox B4 (hoxb4), mRNA GGGCTCTAGGAATAAATTGGACCTTGTTTTTTTTTGGGTGCAATTGAAAAGAAATAAATGAGAATGAGTTCGTTTTTGATCAGCTCCAACTATGTGGACCCCAAGTTTCCGCCCTGTGAGGAGTACTCCCATAGTGATTACTCTCCGGGGTATTACGGCAGCCAGAAGAGGGAGAGCAGTTTTCAGCATGGGGCACCCTACCCTCGATCCGTGTCCAGCAATAGCAGCAGCAGCGCGTCCTACTCCTCCTGCCAAGGATCTGTGCGTCAAAGCGCAAGGCTGCCTCACTCATCTGGACTTGTCCCAGGCGAGAAAGCGCACTTGGAGCCCCACATGCCCACCAGTTCGCCTCCATCCTGCAGCCTCAAGTCCTCAGAGCACAAGCACCCCGACTCCCCGGAGCAGGACCCCGTGGTGTACCCCTGGATGAAGAAGGCGCACATCTCCAAGGCCACTTCCACTTACTCTGATGGAGAAGCCAAGAGATCCCGTACAGCTTACACCAGGCAGCAAGTGCTCGAACTGGAGAAGGAGTTTCACTACAATCGCTACCTGACCCGCAGGCGCAGGGTGGAAATTGCGCACACTTTGCGCCTCTCTGAGCGACAAATTAAGATCTGGTTCCAGAACAGGAGGATGAAGTGGAAGAAAGACCACAAGCTCCCCAATACCAAGATCAAGTCTAACCCTTCTGTGAACCTCCAAATTGCAGGGGGGTCCCCGAATCAGAACAAAGGGAACCATGTCTGCCAATGACATCCCTAGGACTGCTGAAAAAAAAAAAGATAAACTCGACTCTGGTTTTTGTTTCTAATTTATAAAAGGGGAGAAGAGACTTGGCTTGGTCCCCCCCCCCGCTCATCCAGGAGAAGCCTGTAGATAGATTTCAGATTTGGAGAAGATAGATCTATGTTTCATCTTTAATCACGCCAAACCCTGGCCCATTTGTCATGTTTACACTGCGGTACAAAGGCTGAACCTCATCTGACAGAACCAACGCTCATTTTAATAAATGACGCCACCTGTCCCCATGACTGGATCCTTTCTCTCCCCTTTTTTTTCTGCGCGTTATATGGTGACCAAATGCATTGCGGTAGAGTGCTAGCTCTGAGGGTTTCTGTTGCGCAAATCTTATTGTTTGTCAAGTCATTGTTTTTCACTAGCAACCTGTCAACCTCAGACTGGGGACTTGCTTGGATCACACAGTTTGGGGCCTGAGATCACACAGAAGCCAAATTCACAATGCACAATTGTAGCTTCTGGCACTGTAATATATATTTAAGAAATTGATCCTGTCCTCTATAGTAGGCACCCCTACCCACCCAGTTTTATGTGGAAAATGCCTTTACCTGTGTACATAGTTTACCAATAATAAAATATTTTTGCTCAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001116487\|homeobox B4 [Xenopus (Silurana) tropicalis] MRMSSFLISSNYVDPKFPPCEEYSHTDYLPSGHSPEYYGGQKRESSFQHGAPYSRSLSSSSAPYTSCQGSVRQGARLPHSSGLLPGEKAHLESSITPTSPPSCSLIASDHKHPDSPGQDPVVYPWMKKAHISRASSTYSDGEAKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHTLRLSERQIKIWFQNRRMKWKKDHKLPNTKIRSNPSVNLQIAGGSPNQNKGNPVCQ	Refseq >NP_001089733\|homeobox protein Hox-B4 [Xenopus laevis] MRMSSFLISSNYVDPKFPPCEEYSHSDYSPGYYGSQKRESSFQHGAPYPRSVSSNSSSSASYSSCQGSVRQSARLPHSSGLVPGEKAHLEPHMPTSSPPSCSLKSSEHKHPDSPEQDPVVYPWMKKAHISKATSTYSDGEAKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHTLRLSERQIKIWFQNRRMKWKKDHKLPNTKIKSNPSVNLQIAGGSPNQNKGNHVCQ UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.37475	Xl.54392 Xl.86704
Unigene EST Profile		EST Profile	EST Profile EST Profile
GEO data			GEO
Images		37 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HOXB4
mouse		MGI	Hoxb4	All(10) Targeted, knock Out(7) Targeted, other(2)
zebrafish		ZFIN	hoxb4a	1 Lines(s)

Publications
First:		Expression patterns of Hoxb genes in the Xenopus embryo suggest roles in anteroposterior specification of the hindbrain and in dorsoventral patterning of the mesoderm. [Dev Biol 1994]
Most recent:		Hox collinearity - a new perspective. [Int J Dev Biol 2011]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[R] Transcription factor zerknullt and related HOX domain proteins

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.37475.1.S1_at	Xl.15789.1.A1_at
Affymetrix 2.0			Xl2.54392.1.S1_at [+] Xl2.15789.1.A1_at

Symbol legend[+]