zbp1 is a gene in xenopus laevis and xenopus tropicalis, encoding a protein that functions as a cytoplasmic sensor for viral nucleic acids, leading to the activation of innate immune responses. it play...[+]

zbp1 is a gene in xenopus laevis and xenopus tropicalis, encoding a protein that functions as a cytoplasmic sensor for viral nucleic acids, leading to the activation of innate immune responses. it plays a role in detecting viral rna, triggering signaling pathways that result in the production of interferons and pro-inflammatory cytokines, contributing to antiviral defense mechanisms. the protein may also be involved in regulating cell death pathways, such as apoptosis, in response to viral infection. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD