Gene Symbol: foxa2 Gene Name: forkhead box A2 Synonyms: hnf3b, hnf3beta, hnf3-beta Add Xenopus synonyms Gene Function: forkhead domain transcription factor Interactants: sox17a(7) , hhex(6) , odc1(6) , shh(6) , foxa4(5) , pdx1(5) , gli1(4) View All	1/3

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_204092|Xenopus (Silurana) tropicalis forkhead box A2 (foxa2), mRNA TTTTAAACTGCCAGGCACTCAGCTTCCAGTATGCTCGGGGCTGTGAAAATGGAAGGACACGAAGCCACAGACTGGAGCAGCTACTACGGGGAACCCGAGGCTTACTCCTCGGTGGGTAACATGAACGCCGGGCTGAGCATGAACCCCATGAACACGTACATGAGCATGTCTGCTATGAGCACCTCGGCCAACATGACCGCCGGCTCCATGAACATGTCCTATGTGAATACTGGGATGAGCCCATCGCTCACCGGCATGTCTCCTGGCACCGGGGCAATGACTGGAATGGGCACCGGGGTAGCCAGTATGGCAAGTCACCTCAGCCCCAGTATGAGCCCGATGAGTGCCCAGGCTACTTCTATGAATGCCCTGGCACCCTATACCAACATGAACTCAATGAGCCCAATCTATGGACAGTCCAACATCAACAGATCCAGGGACCCCAAGACTTACAGGCGCAGTTATACGCATGCGAAGCCCCCCTACTCGTACATCTCGCTCATCACCATGGCGATCCAGCAGTCCCCCAACAAGATGCTCACTCTCAGCGAGATTTATCAGTGGATCATGGACCTGTTTCCTTTCTACAGGCAGAACCAGCAGCGCTGGCAGAACTCTATCCGCCATTCTCTTTCCTTCAATGACTGTTTTCTCAAGGTGCCCAGGTCCCCTGACAAGCCCGGAAAGGGCTCCTTCTGGACCCTACACCCCGATTCGGGCAACATGTTTGAGAATGGCTGTTACCTGAGGCGACAGAAACGCTTCAAGTGCGAGAAAAAGCCCAGCCTTAGAGAAGGGGGAGGCAAGAAACTCTCAGAAGGGTCATCGAGTGTGGGCTCTGCAGCCAACAGCAGCTCTGAGAGCTCAGTGGGCAATGAGTCCCCGCACTCCAGCTCGTCCCCCTGCCAGGAGCAGAAGAGGTCTCTAGTAGATATGAAGTCCAGCCAAGGCTTAAGCCCAGACCATGCAGCCTCCCCAGCCTCCCAAGCCCAGCACTTGCTTTCCCAGCACCACTCTGTCTTGTCCCATGAAGCCCAGTCCCACCTCAAACCAGAACACCATTATTCTTTCAACCACCCATTCTCCATCAACAACCTCATGTCCTCAGAGCAACAGCACCACCATCACCACCACCACAACCACCATCATCACCATAAAATGGACTTAAAAGCTTATGAACAGGTGATGCACTACTCTGGTTACGGGTCCCCCATGACTGGCAGCCTGGCAATGAGCACAGTAACAAACAAAAGTGGCTTAGAGTCTTCACCTATTTCCAGTGACACCTCATACTATCAAGGTGTGTATTCTAGACCTATCATGAACTCCTCATAGACTTTCTACCATGGACTTGTCACCTGGGCTCTGTGTATATAATATTAAGAAGAAAAACAACATAGTATGTGTCTACATTCCTATTGAATTGTACAGTCCCCCGAGTTTGTTTCTGTATAGGAGCTTAGCTTGTTAAGCTATGTTTGATTTGGGTGCTTTTCTTTGGCAAGGAGTATATTTTTGTGAAAGTGACGGATCCTAATTTTTCTGTGTGAAATCTGTTAATTTTCCCTAAGGACCAAAATTGTGTGATATTGGTAATGTTAAAAAAAACAGAAACGGAATATATTGATGTAATTGAAAAAAAAGATGTTTTTTTTTTTTATTTGTTTGGGGGAGATGCTTGAAACTGGTTAATTTATGGTTTCTGTATGTTTTATTTATGACTGCTGTATGTATTCTGGCCATAACCGGCCGGTTTAACAAACTCTATTAAAAAATGAATTGGCAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001172158|Xenopus laevis forkhead box A2 (foxa2), mRNA ATGCTTGGGGCTGTGAAAATGGAAGGACACGAAGCTACAGATTGGAGCAGCTACTACGGGGAAGCAGAGGCTTACTCGTCGGTGGGCAATATGAACGCTGGGCTGAGCATGAATCCCATGAACACGTACATGAGCATGTCTGCTATGAGGACCTCGGCCAACATGACCGCCAGCTCCATGAACATGTCCTATGTGAACACGGGCATGAGCCCATCACTGACCGGCATGTCTCCTGGCACCGGGGCAATGACTGGCATGGGCACGGGGGTCCCCAGCATGGCAAGTCACCTGAGCCCCAGTATGATCCCGATGAGCGCCCAGACAACTGCAATGAATGCCCTGGCACCCTATACCAACATCAACTCCATGAGCCCAATTTATGGACAGTCCAACATCAACAGATCCAGGGACCCCAAAACTTACCGGCGAAGTTACACACATGCCAAGCCCCCCTACTCATACATCTCGCTCATCACCATGGCCATCCAGCAGTCCCCCAACAAGATGCTGACGCTGAGTGAGATCTATCAGTGGATCATGGACCTGTTCCCTTTCTACAGGCAGAACCAGCAGCGATGGCAGAACTCTATCCGCCATTCCCTTTCCTTTAATGACTGTTTCCTCAAGGTGCCCAGGTCCCCGGACAAGCCTGGAAAAGGTTCCTTCTGGACCCTACACCCTGATTCGGGCAACATGTTTGAGAACGGCTGTTACCTGCGGCGACAGAAACGCTTCAAGTGCGAGAAAAAGCCCAGCCTTAGGGAAGGGGGAGGCAAGAAACTTTCAGAAGGGGCATCGAGTGTGGGCTCTGCGGCCAACAGCAGCTCTGAAAGCTCAGTGGGCAATGAGTCTCCGCACTCCAGCTCGTCTCCCTGCCAGGAGCAGAAGAGGTCTCTTGTAGATATGAAGTCCAGCCAAGGCTTGAGCCCAAAGCATGCCACCTCCCCAGCCTCCCAAGCCCAGCACTTGCTTTCCCAGCACCATTCTGTCCTGTCCCATGAAGCCCAGTCCCACCTCAAACCAGAACACCATTATTCTTTCAACCACCCATTTTCCATCAACAATCTCATGTCCTCGGAGCAACAGCACCACCACCACCATCACCACAACCACCATCACCACCATAAAATGGACTTGAAAGCCTACGAACAGGTGATGCACTACTCTAGTTACGGGTCCCCCATGGCTGGCAGCCTGGCAATGAGCACAGTAACAAACAAAAGTGGCTTAGAGTCTTCACCTATTACCAGTGACACCTCATACTATCAAGGTGGGTATTCTAGACCTATCATGAACTCCTCATAG
Protein		Refseq >NP_989423|forkhead box protein A2 [Xenopus (Silurana) tropicalis] MLGAVKMEGHEATDWSSYYGEPEAYSSVGNMNAGLSMNPMNTYMSMSAMSTSANMTAGSMNMSYVNTGMSPSLTGMSPGTGAMTGMGTGVASMASHLSPSMSPMSAQATSMNALAPYTNMNSMSPIYGQSNINRSRDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKKPSLREGGGKKLSEGSSSVGSAANSSSESSVGNESPHSSSSPCQEQKRSLVDMKSSQGLSPDHAASPASQAQHLLSQHHSVLSHEAQSHLKPEHHYSFNHPFSINNLMSSEQQHHHHHHHNHHHHHKMDLKAYEQVMHYSGYGSPMTGSLAMSTVTNKSGLESSPISSDTSYYQGVYSRPIMNSS UniProtKB	Refseq >NP_001165629|forkhead box protein A2-A [Xenopus laevis] MLGAVKMEGHEATDWSSYYGEAEAYSSVGNMNAGLSMNPMNTYMSMSAMRTSANMTASSMNMSYVNTGMSPSLTGMSPGTGAMTGMGTGVPSMASHLSPSMIPMSAQTTAMNALAPYTNINSMSPIYGQSNINRSRDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKKPSLREGGGKKLSEGASSVGSAANSSSESSVGNESPHSSSSPCQEQKRSLVDMKSSQGLSPKHATSPASQAQHLLSQHHSVLSHEAQSHLKPEHHYSFNHPFSINNLMSSEQQHHHHHHHNHHHHHKMDLKAYEQVMHYSSYGSPMAGSLAMSTVTNKSGLESSPITSDTSYYQGGYSRPIMNSS UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.8107	[+] Xl.40286
Unigene EST Profile		EST Profile
GEO data			GEO
Images		25 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	FOXA2
mouse		MGI	Foxa2	All(12) Targeted, knock Out(2) Targeted, other(9)
zebrafish		ZFIN	foxa2	4 Lines(s)

Publications
First:		A fork head related multigene family is transcribed in Xenopus laevis embryos. [Int J Dev Biol 1996]
Most recent:		The genomic structure and the expression profile of the Xenopus laevis transthyretin gene. [Gene 2012]
		View All Papers 7 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] Forkhead/HNF-3-related transcription factor (alt_id KOG:3563)

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.8107.1.S1_at
Affymetrix 2.0			Xl2.55736.1.S1_at [+] Xl2.40286.1.A1_at

Symbol legend[+]

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   - Literature Or Expression Images